European Journal of Chemistry

Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution



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Hiroshi Sakiyama
Hidetatsu Inoue
Md.Kudrat-E-Zahan Md.Kudrat-E-Zahan
Shoichi Hueki
Naohisa Tachiya
Yuzo Nishida

Abstract

It is known that 5-aminolevulinic acid (5-ALA) is not stable in an aqueous solution because of the auto-condensation reaction between two 5-ALA molecules; however, in this study, 5-ALA was stabilized by the zinc(II) ion in an aqueous solution of neutral pH. This stabilization effect was ascertained by UV-Vis Spectroscopy and 1H and 13C NMR Spectroscopy.

1_4_373_376_800


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Sakiyama, H.; Inoue, H.; Md.Kudrat-E-Zahan, M.-E.-Z.; Hueki, S.; Tachiya, N.; Nishida, Y. Stabilization of 5-Aminolevulinic Acid by the zinc(II) Ion in an Aqueous Solution. Eur. J. Chem. 2010, 1, 373-376.

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