Synthesis and antimicrobial evaluation of some 1,2,4-triazolo[1,5-a]pyridine, pyrimidine sulfonamides and sulfinyl derivatives

Fatma Fakhry Abdel-Motaal; Mohamed Abd-Elmonem Raslan

doi:10.5155/eurjchem.5.3.481-487.1054

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Published: Sep 30, 2014

DOI: https://doi.org/10.5155/eurjchem.5.3.481-487.1054

Keywords:

Sulfinyl, Pyrimidine, Benzooxazole, Sulfonamides, Benzimidazole, Triazolopyridine

Section

Research Article

Issue

Vol. 5 No. 3 (2014): September 2014

Dates

Received 2014-03-18
Accepted 2014-04-24
Published 2014-09-30

Fatma Fakhry Abdel-Motaal

Botany Department, Faculty of Science, Aswan University, 81528 Aswan, Egypt

Mohamed Abd-Elmonem Raslan

Chemistry Department, Faculty of Science, Aswan University, 81528 Aswan, Egypt

Abstract

Several new substituted sulfonamides and sulfinyl compound derivatives were obtained by the reaction of 2-thioxo-1,2,4-triazolo[1,5-a]pyridine and pyrimidine thiol derivatives with (2-chloromethyl)benzimidazole and/or (2-chloromethyl)benzooxazole. Structures of the newly synthesized products have been deduced on the basis of spectral and analytical data. The synthesized compounds were screened for their antimicrobial activity.

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Abdel-Motaal, F. F.; Raslan, M. A.-E. Synthesis and Antimicrobial Evaluation of Some 1,2,4-triazolo[1,5-a]pyridine, Pyrimidine Sulfonamides and Sulfinyl Derivatives. Eur. J. Chem. 2014, 5, 481-487.

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