European Journal of Chemistry 2010, 1(3), 232-235 | doi: https://doi.org/10.5155/eurjchem.1.3.232-235.112 | Get rights and content

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DABCO as an efficient catalyst for the synthesis of 3-cyano-2(1H)-pyridinones and their 2-imino analogues


Yahia Shirazi Beheshtia (1) , Maliheh Khorshidi (2) , Majid Momahed Heravi (3,*) , Bita Baghernejad (4)

(1) Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, IR19569, Iran
(2) Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, IR19569, Iran
(3) Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, IR19569, Iran
(4) Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, IR19569, Iran
(*) Corresponding Author

Received: 17 May 2010 | Revised: 03 Aug 2010 | Accepted: 08 Jul 2010 | Published: 29 Sep 2010 | Issue Date: September 2010

Abstract


3-cyano-2(1H)-pyridinones and their 2-imino analogues have been synthesized in good yields via a one-pot multi-component reaction of 3,4-dimethoxyacetophenone, malononitrile or ethylcyanoacetate, ammonium acetate and various aldehydes in the presence of  1,4-diaza-bicyclo[2,2,2]octane (DABCO) in ethanol. DABCO has been widely used as a catalyst for the organic reactions and we selected it as an efficient catalyst to synthesis of 3-cyano-pyridines. All products were characterized by melting point, IR, 1H NMR and GC/MS studies.

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Keywords


1,4-Diaza-bicyclo[2,2,2]octane; Cyano-2(1H)-pyridinones; Cyano-2(1H)-iminopyridines; 3,4-Dimethoxyacetophenone; DABCO; Catalyst

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DOI: 10.5155/eurjchem.1.3.232-235.112

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Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran

Citations

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How to cite


Beheshtia, Y.; Khorshidi, M.; Heravi, M.; Baghernejad, B. Eur. J. Chem. 2010, 1(3), 232-235. doi:10.5155/eurjchem.1.3.232-235.112
Beheshtia, Y.; Khorshidi, M.; Heravi, M.; Baghernejad, B. DABCO as an efficient catalyst for the synthesis of 3-cyano-2(1H)-pyridinones and their 2-imino analogues. Eur. J. Chem. 2010, 1(3), 232-235. doi:10.5155/eurjchem.1.3.232-235.112
Beheshtia, Y., Khorshidi, M., Heravi, M., & Baghernejad, B. (2010). DABCO as an efficient catalyst for the synthesis of 3-cyano-2(1H)-pyridinones and their 2-imino analogues. European Journal of Chemistry, 1(3), 232-235. doi:10.5155/eurjchem.1.3.232-235.112
Beheshtia, Yahia, Maliheh Khorshidi, Majid Momahed Heravi, & Bita Baghernejad. "DABCO as an efficient catalyst for the synthesis of 3-cyano-2(1H)-pyridinones and their 2-imino analogues." European Journal of Chemistry [Online], 1.3 (2010): 232-235. Web. 29 May. 2023
Beheshtia, Yahia, Khorshidi, Maliheh, Heravi, Majid, AND Baghernejad, Bita. "DABCO as an efficient catalyst for the synthesis of 3-cyano-2(1H)-pyridinones and their 2-imino analogues" European Journal of Chemistry [Online], Volume 1 Number 3 (29 September 2010)

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European Journal of Chemistry 2010, 1(3), 232-235 | doi: https://doi.org/10.5155/eurjchem.1.3.232-235.112 | Get rights and content

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