European Journal of Chemistry

Synthesis, characterization and antimicrobial investigation of Rh(III), Ru(III) and Ag(I) complexes with some derivatives of 3-amino-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones

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Ramu Guda
Kumara Swamy Battula
Srujana Muthadi
Sarika Kasarla
Rambabu Palabindela
Rajashekar Korra
Thampu Raja Komuraiah
Mamatha Kasula


The reaction of 2,3-disubstituted mercapto quinazolines with 2-hydroxy benzaldehyde (HBAMQ) (1), 2-hydroxy naphthaldehyde (HNAMQ) (2), pyridine-2-carboxaldehyde (PMAMQ) (3) and thiophen-2-carboxaldehyde (TMAMQ) (4), and with metals like Rh(III), Ru(III), and Ag(I) in the presence of piperidine resulted in the formation of their respective complexes by physicochemical methods. The newly synthesized complexes were characterized by elemental analysis, magnetic data, and spectroscopic techniques like UV-Visible, IR and 1H NMR, respectively. These compounds were also evaluated for their antimicrobial activities.

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Guda, R.; Battula, K. S.; Muthadi, S.; Kasarla, S.; Palabindela, R.; Korra, R.; Komuraiah, T. R.; Kasula, M. Synthesis, Characterization and Antimicrobial Investigation of Rh(III), Ru(III) and Ag(I) Complexes With Some Derivatives of 3-Amino-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-Ones. Eur. J. Chem. 2016, 7, 334-340.

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