European Journal of Chemistry 2016, 7(4), 431-435. doi:10.5155/eurjchem.7.4.431-435.1485

Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition


Shuddhodan Narhari Kadam (1) , Ajay Niwruttirao Ambhore (2) , Milind Vithalrao Gaikwad (3) , Rahul Datta Kamble (4) , Shrikant Vasantappa Hese (5) , Madhav Janardan Hebade (6) , Bhaskar Sadashiv Dawane (7,*)

(1) School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, India
(2) School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, India
(3) School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, India
(4) Amruteshwar Arts, Commerce and Science College, Vinzar, Tal. Velhe Dist., Pune, 412213, India
(5) School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, India
(6) School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, India
(7) School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, India
(*) Corresponding Author

Received: 08 Aug 2016, Accepted: 01 Oct 2016, Published: 31 Dec 2016

Abstract


The present report describes a microwave assisted convenient and efficient protocol for the synthesis of new 6-(4-substituted-phenyl)-3-methylimidazo[2,1-b]thiazole-2-carbohydra- zide derivatives. The current method holds a tag of green synthesis by virtue of catalyst and solvent free media. Moreover, the procedure offers excellent yield and purity of the products under mild condition compared with conventional method.


Keywords


Thiazole; Imidazol; Microwave; Carbohydrazide; Multi-component; Solvent free reaction

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DOI: 10.5155/eurjchem.7.4.431-435.1485

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How to cite


Kadam, S.; Ambhore, A.; Gaikwad, M.; Kamble, R.; Hese, S.; Hebade, M.; Dawane, B. Eur. J. Chem. 2016, 7(4), 431-435. doi:10.5155/eurjchem.7.4.431-435.1485
Kadam, S.; Ambhore, A.; Gaikwad, M.; Kamble, R.; Hese, S.; Hebade, M.; Dawane, B. Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition. Eur. J. Chem. 2016, 7(4), 431-435. doi:10.5155/eurjchem.7.4.431-435.1485
Kadam, S., Ambhore, A., Gaikwad, M., Kamble, R., Hese, S., Hebade, M., & Dawane, B. (2016). Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition. European Journal of Chemistry, 7(4), 431-435. doi:10.5155/eurjchem.7.4.431-435.1485
Kadam, Shuddhodan, Ajay Niwruttirao Ambhore, Milind Vithalrao Gaikwad, Rahul Datta Kamble, Shrikant Vasantappa Hese, Madhav Janardan Hebade, & Bhaskar Sadashiv Dawane. "Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition." European Journal of Chemistry [Online], 7.4 (2016): 431-435. Web. 17 Sep. 2019
Kadam, Shuddhodan, Ambhore, Ajay, Gaikwad, Milind, Kamble, Rahul, Hese, Shrikant, Hebade, Madhav, AND Dawane, Bhaskar. "Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition" European Journal of Chemistry [Online], Volume 7 Number 4 (31 December 2016)

DOI Link: https://doi.org/10.5155/eurjchem.7.4.431-435.1485

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