European Journal of Chemistry

Microwave assisted multicomponent reaction: An environmentally benign protocol for the synthesis of substituted imidazo[2,1-b]thiazole-2-carbohydrazide derivatives under solvent free condition



Main Article Content

Shuddhodan Narhari Kadam
Ajay Niwruttirao Ambhore
Milind Vithalrao Gaikwad
Rahul Datta Kamble
Shrikant Vasantappa Hese
Madhav Janardan Hebade
Bhaskar Sadashiv Dawane

Abstract

The present report describes a microwave assisted convenient and efficient protocol for the synthesis of new 6-(4-substituted-phenyl)-3-methylimidazo[2,1-b]thiazole-2-carbohydra- zide derivatives. The current method holds a tag of green synthesis by virtue of catalyst and solvent free media. Moreover, the procedure offers excellent yield and purity of the products under mild condition compared with conventional method.


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Kadam, S. N.; Ambhore, A. N.; Gaikwad, M. V.; Kamble, R. D.; Hese, S. V.; Hebade, M. J.; Dawane, B. S. Microwave Assisted Multicomponent Reaction: An Environmentally Benign Protocol for the Synthesis of Substituted imidazo[2,1-b]thiazole-2-Carbohydrazide Derivatives under Solvent Free Condition. Eur. J. Chem. 2016, 7, 431-435.

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