European Journal of Chemistry 2017, 8(1), 13-14 | doi: https://doi.org/10.5155/eurjchem.8.1.13-14.1525 | Get rights and content

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Microwave assistant synthesis of trans-4-nitrostilbene derivatives in solvent free condition


Ming Jun Cen (1) , Yu Wang (2) , Yong Wu He (3,*)

(1) Department of Chemistry, Hebei University of Engineering, Handan, 056038, China
(2) Department of Chemistry, Hebei University of Engineering, Handan, 056038, China
(3) Department of Chemistry, Hebei University of Engineering, Handan, 056038, China
(*) Corresponding Author

Received: 23 Dec 2016 | Revised: 13 Jan 2017 | Accepted: 14 Jan 2017 | Published: 31 Mar 2017 | Issue Date: March 2017

Abstract


A general method for the synthesis of trans-4-nitrostilbenes has been developed. The trans-4-nitrostilbene could be synthesized in good yields under microwave irradiation within 10 min through Perkin reaction by using 4-nitrophenylacetic acid, benzaldehydes and pyrrolidine.


Keywords


Stilbene; Perkin reaction; Trans-4-nitrostilbene; Microwave chemistry; Solvent free condition; Microwave irradiation

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DOI: 10.5155/eurjchem.8.1.13-14.1525

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Funding information


The Research Foundation of Administration of Science and Technology of Handan, P. R. China (Project No: 1629209045-4) and Foundations of Hebei University of Engineering, China

Citations

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[1]. Dushyant V. Patel, Nirav R. Patel, Ashish M. Kanhed, Divya M. Teli, Kishan B. Patel, Prashant D. Joshi, Sagar P. Patel, Pallav M. Gandhi, Bharat N. Chaudhary, Navnit K. Prajapati, Kirti V. Patel, Mange Ram Yadav
Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents
Bioorganic Chemistry  101, 103977, 2020
DOI: 10.1016/j.bioorg.2020.103977
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How to cite


Cen, M.; Wang, Y.; He, Y. Eur. J. Chem. 2017, 8(1), 13-14. doi:10.5155/eurjchem.8.1.13-14.1525
Cen, M.; Wang, Y.; He, Y. Microwave assistant synthesis of trans-4-nitrostilbene derivatives in solvent free condition. Eur. J. Chem. 2017, 8(1), 13-14. doi:10.5155/eurjchem.8.1.13-14.1525
Cen, M., Wang, Y., & He, Y. (2017). Microwave assistant synthesis of trans-4-nitrostilbene derivatives in solvent free condition. European Journal of Chemistry, 8(1), 13-14. doi:10.5155/eurjchem.8.1.13-14.1525
Cen, Ming, Yu Wang, & Yong Wu He. "Microwave assistant synthesis of trans-4-nitrostilbene derivatives in solvent free condition." European Journal of Chemistry [Online], 8.1 (2017): 13-14. Web. 16 Jan. 2021
Cen, Ming, Wang, Yu, AND He, Yong. "Microwave assistant synthesis of trans-4-nitrostilbene derivatives in solvent free condition" European Journal of Chemistry [Online], Volume 8 Number 1 (31 March 2017)

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