

NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines
Gajanan Gopinath Mandawad (1)




(1) Department of Chemistry, Maharashtra Udayagiri College, Udgir-413517, Maharashtra, India
(2) Department of Chemistry, Sir Sayyed College, Aurangabad-431001, Maharashtra, India
(3) Organic Research Laboratory, Loknete Vyankatrao Hirey College, Nashik-422003, Maharashtra, India
(4) Department of Chemistry, Karamsibhai Jethabhai Somaiya College, Kopargaon-423601, Maharashtra, India
(*) Corresponding Author
Received: 19 Jul 2020 | Revised: 05 Sep 2020 | Accepted: 14 Sep 2020 | Published: 31 Dec 2020 | Issue Date: December 2020
Abstract
A simple and eloquent procedure for the synthesis of a new series of thienyl benzo[b]1,4-diazepines is reported. They were synthesized by the condensation of o-phenylenediamine (o-PDA) with distinct hetero chalcones using NaOH in polyethylene glycol (PEG-400) as green and alternative reaction solvent. The significances of this present method are shorter reaction time, easy work-up, high yields, and mild reaction conditions. Furthermore, this method is environment friendly and without use of an expensive catalyst. The all newly synthesized compounds are characterized by the spectroscopic methods.
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DOI: 10.5155/eurjchem.11.4.276-279.2009
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