European Journal of Chemistry 2020, 11(4), 276-279 | doi: https://doi.org/10.5155/eurjchem.11.4.276-279.2009 | Get rights and content

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NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines


Gajanan Gopinath Mandawad (1) orcid , Baseer Mubeen Shaikh (2) orcid , Santosh Subhash Chobe (3) orcid , Shankaraiah Guruvaiah Konda (4,*) orcid

(1) Department of Chemistry, Maharashtra Udayagiri College, Udgir-413517, Maharashtra, India
(2) Department of Chemistry, Sir Sayyed College, Aurangabad-431001, Maharashtra, India
(3) Organic Research Laboratory, Loknete Vyankatrao Hirey College, Nashik-422003, Maharashtra, India
(4) Department of Chemistry, Karamsibhai Jethabhai Somaiya College, Kopargaon-423601, Maharashtra, India
(*) Corresponding Author

Received: 19 Jul 2020 | Revised: 05 Sep 2020 | Accepted: 14 Sep 2020 | Published: 31 Dec 2020 | Issue Date: December 2020

Abstract


A simple and eloquent procedure for the synthesis of a new series of thienyl benzo[b]1,4-diazepines is reported. They were synthesized by the condensation of o-phenylenediamine (o-PDA) with distinct hetero chalcones using NaOH in polyethylene glycol (PEG-400) as green and alternative reaction solvent. The significances of this present method are shorter reaction time, easy work-up, high yields, and mild reaction conditions. Furthermore, this method is environment friendly and without use of an expensive catalyst. The all newly synthesized compounds are characterized by the spectroscopic methods.


Keywords


Chalcones; Green synthesis; NaOH/PEG-400; o-Phenylenediamine; Operational simplicity; Benzo[b]1,4-diazepines

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DOI: 10.5155/eurjchem.11.4.276-279.2009

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How to cite


Mandawad, G.; Shaikh, B.; Chobe, S.; Konda, S. Eur. J. Chem. 2020, 11(4), 276-279. doi:10.5155/eurjchem.11.4.276-279.2009
Mandawad, G.; Shaikh, B.; Chobe, S.; Konda, S. NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines. Eur. J. Chem. 2020, 11(4), 276-279. doi:10.5155/eurjchem.11.4.276-279.2009
Mandawad, G., Shaikh, B., Chobe, S., & Konda, S. (2020). NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines. European Journal of Chemistry, 11(4), 276-279. doi:10.5155/eurjchem.11.4.276-279.2009
Mandawad, Gajanan, Baseer Mubeen Shaikh, Santosh Subhash Chobe, & Shankaraiah Guruvaiah Konda. "NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines." European Journal of Chemistry [Online], 11.4 (2020): 276-279. Web. 24 Jan. 2022
Mandawad, Gajanan, Shaikh, Baseer, Chobe, Santosh, AND Konda, Shankaraiah. "NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines" European Journal of Chemistry [Online], Volume 11 Number 4 (31 December 2020)

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