NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines

Gajanan Gopinath Mandawad; Baseer Mubeen Shaikh; Santosh Subhash Chobe; Shankaraiah Guruvaiah Konda

doi:10.5155/eurjchem.11.4.276-279.2009

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Published: Dec 31, 2020

DOI: https://doi.org/10.5155/eurjchem.11.4.276-279.2009

Keywords:

Chalcones, Green synthesis, NaOH/PEG-400, o-Phenylenediamine, Operational simplicity, Benzo[b]1, 4-diazepines

Section

Research Article

Issue

Vol. 11 No. 4 (2020): December 2020

Dates

Received 2020-07-19
Accepted 2020-09-14
Published 2020-12-31

Gajanan Gopinath Mandawad

Department of Chemistry, Maharashtra Udayagiri College, Udgir-413517, Maharashtra, India

http://orcid.org/0000-0002-5317-2637

Baseer Mubeen Shaikh

Department of Chemistry, Sir Sayyed College, Aurangabad-431001, Maharashtra, India

http://orcid.org/0000-0001-8073-3332

Santosh Subhash Chobe

Organic Research Laboratory, Loknete Vyankatrao Hirey College, Nashik-422003, Maharashtra, India

http://orcid.org/0000-0001-5522-2522

Shankaraiah Guruvaiah Konda

Department of Chemistry, Karamsibhai Jethabhai Somaiya College, Kopargaon-423601, Maharashtra, India

http://orcid.org/0000-0002-1939-6784

Abstract

A simple and eloquent procedure for the synthesis of a new series of thienyl benzo[b]1,4-diazepines is reported. They were synthesized by the condensation of o-phenylenediamine (o-PDA) with distinct hetero chalcones using NaOH in polyethylene glycol (PEG-400) as green and alternative reaction solvent. The significances of this present method are shorter reaction time, easy work-up, high yields, and mild reaction conditions. Furthermore, this method is environment friendly and without use of an expensive catalyst. The all newly synthesized compounds are characterized by the spectroscopic methods.

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How to Cite

(1)

Mandawad, G. G.; Shaikh, B. M.; Chobe, S. S.; Konda, S. G. NaOH/PEG-400:/An/Eloquent/System/for/the/Synthesis/of/New/Thienyl/benzo[b]1,4-Diazepines. Eur. J. Chem. 2020, 11, 276-279.

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