

Synthesis, crystal structures and antimicrobial activity of palladium metal complexes of sulfonyl hydrazone ligands
Samina Karimkha Tadavi (1)





(1) Department of Chemistry, Jashbhai Muljibhai Patel Arts, Commerce and Science College, Bhandara, Maharashtra, 441904, India
(2) School of Chemical Sciences, Kavayitri Bahinabai Chaudhari North Maharashtra University, Jalgaon, Maharashtra, 425001, India
(3) School of Life Sciences, Kavayitri Bahinabai Chaudhari North Maharashtra University, Jalgaon, Maharashtra, 425001, India
(4) Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore, 560012, India
(5) Department of Chemistry, Faculty of BP Arts, SMA Science and KKC Commerce College Chalisgaon, Maharashtra, 424101, India
(*) Corresponding Author
Received: 31 Aug 2020 | Revised: 07 Nov 2020 | Accepted: 22 Nov 2020 | Published: 31 Dec 2020 | Issue Date: December 2020
Abstract
Palladium complexes of sulfonyl hydrazone based ligands have been prepared by refluxing with the corresponding ligands and Pd(II) salt in 2:1 ratio. The compounds have been characterized by FT-IR and UV-Vis spectroscopic methods. The crystal structure of the prepared palladium complexes has been determined by single-crystal X-ray crystallographic technique. Crystal data for C40H50N4O6PdS2 (PMHT-Pd(II) complex): triclinic, space group P-1 (no. 2), a = 7.1561(6) Å, b = 12.1300(11) Å, c = 12.6117(17) Å, α = 63.498(11)°, β = 86.694(9)°, γ = 81.451(7)° and Z = 1. The final R1 was 0.0699 (I > 2σ(I)) and wR2 was 0.1834 (all data). Crystal data for C36H42N4O6PdS2 (PTHC-Pd(II) complex): monoclinic, space group P21/n (no. 14), a = 8.6726(2) Å, b = 20.8824(4) Å, c = 10.3351(2) Å, β = 104.429(2)° and Z = 2. The final R1 was 0.0344 (I > 2σ(I)) and wR2 was 0.0840 (all data). Crystal data for C36H42N4O6PdS2 (PTHT-Pd(II) complex): monoclinic, space group P21/n (no. 14), a = 9.7658(2) Å, b = 10.0488(3) Å, c = 18.7714(4) Å, β = 99.602(2)° and Z = 2. The final R1 was 0.0334 (I > 2σ(I)) and wR2 was 0.0832 (all data). Crystal data for C40H50N4O6PdS2 (PMHC-Pd(II) complex): triclinic, space group P-1 (no. 2), a = 10.2070(9) Å, b = 12.1841(13) Å, c = 16.8879(19) Å, α = 109.005(6)°, β = 90.061(5)°, γ = 99.032(5)° and Z = 2. The final R1 was 0.0822 (I > 2σ(I)) and wR2 was 0.2293 (all data). The single-crystal structure data showed a good agreement with the experimental results. The synthesized complexes were screened for their in vitro antibacterial activity against one Gram-negative (Escherichia coli) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains and for in vitro antifungal activity against Aspergillus niger, Aspergillus flavus and Aspergillus fumigatus. The PTHC-Pd(II) complex possesses the nearby significant antifungal activity analogous to the standard drug fluconazole against selected fungal strains Aspergillus niger, Aspergillus Flavus and Aspergillus fumigatus as well as the same complex showed the antibacterial activity for Staphylococcus aureus as comparable to standard ofloxacin drug.
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DOI: 10.5155/eurjchem.11.4.377-384.2040
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Sophisticated Analytical Instrumentation Facility, Indian Institute of Technology, Madras and Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore, India.
Citations
[1]. Rahul T. Bhoi, Jamatsing D. Rajput, Ratnamala S. Bendre
An efficient synthesis of rearranged new biologically active benzimidazoles derived from 2-formyl carvacrol
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DOI: 10.1007/s11164-021-04601-9

[2]. M. Muthuppalani, Ahmed Al Otaibi, S. Balasubramaniyan, S. Manikandan, P. Manimaran, G. Mathubala, A. Manikandan, Tahseen Kamal, Anish Khan, Hadi M. Marwani, Khalid A. Alamry, Abdullah M. Asiri
An in-vitro anti-inflammatory and anti-microbial essential on Ni(II), Cd(II) mixed ligand complexes by using 2,4-dinitrophenyl hydrazine and dimethylglyoxime
Journal of King Saud University - Science 34(5), 102114, 2022
DOI: 10.1016/j.jksus.2022.102114

[3]. Rahul T. Bhoi, Chaitu N. Bhoi, Sumit R. Nikume, Ratnamala S. Bendre
Design, synthesis, and in silico studies of benzimidazoles of thymol as potent antiplasmodial and antimicrobial agents
Results in Chemistry 6, 101112, 2023
DOI: 10.1016/j.rechem.2023.101112

[4]. Smita S. Patil, Samina K. Tadavi, Amol Dikundwar, Ratnamala S. Bendre
The transition metal complexes of Fe(II), Ni(II) and Cu(II) derived from phthalazine based ligands: Synthesis, crystal structures and biological activities
Journal of Molecular Structure 1247, 131293, 2022
DOI: 10.1016/j.molstruc.2021.131293

[5]. M. Muthuppalani, Ahmed Al Otaibi, S. Balasubramaniyan, S. Manikandan, P. Manimaran, G. Mathubala, A. Manikandan, Muhammad Nadeem Arshad, Madhu Puttegowda, Hajer Saeed Alorfi, Anish Khan, Abdullah M. Asiri, Mohammed M. Rahman
Synthesis, Characterization and Bio-Potential Activities of Co(II) and Ni(II) Complexes with O and N Donor Mixed Ligands
Crystals 12(3), 326, 2022
DOI: 10.3390/cryst12030326

References
[1]. Ozbek, N.; Alyar, S.; Karacan, N. J. Mol. Struc. 2009, 938(1-3), 48-53.
https://doi.org/10.1016/j.molstruc.2009.09.002
[2]. Lima, L. M.; Amarante, E. G.; Miranda, A. L. P.; Fraga, C. A. M.; Barreiro, E. J. Pharm. Pharmacol. Commun. 1999, 5(12), 673-678.
https://doi.org/10.1211/146080899128734370
[3]. Alyar, S.; Karacan, N. J. Enzyme Inh. Med. Chem. 2009, 24(4), 986-992.
https://doi.org/10.1080/14756360802561220
[4]. Alyar, H.; Unal, A.; Ozbek, N.; Alyar, S.; Karacan, N. Spectrochim. Acta A 2012, 91, 39-47.
https://doi.org/10.1016/j.saa.2012.01.065
[5]. Bildirici, I.; Sener, A.; Tozlu, I. Med. Chem. Res. 2007, 16(7-9), 418-426.
https://doi.org/10.1007/s00044-007-9082-z
[6]. Alyar, S.; Ozbek, N.; Iskeleli, N. O.; Karacan, N. Med. Chem. Res. 2012, 22(5), 2051-2060.
https://doi.org/10.1007/s00044-012-0171-2
[7]. Alyar, H.; Alyar, S.; Unal, A.; Ozbek, N.; Sahin, E.; Karacan, N. J. Mol. Struc. 2012, 1028, 116-125.
https://doi.org/10.1016/j.molstruc.2012.06.046
[8]. Ozdemir, U. O.; Akkaya, N.; Ozbek, N. Inorg. Chim. Acta 2013, 400, 13-19.
https://doi.org/10.1016/j.ica.2013.01.031
[9]. Murtaza, S.; Shamim, S.; Kousar, N.; Tahir, M. N.; Sirajuddin, M.; Rana, U. A. J. Mol. Struc. 2016, 1107, 99-108.
https://doi.org/10.1016/j.molstruc.2015.11.046
[10]. Bruker. SAINT. Bruker AXS Inc., Madison, Wisconsin, USA, 2004.
[11]. Bruker. XPREP. Bruker AXS Inc., Madison, Wisconsin, USA, 2004.
[12]. Sheldrick, G. M. Acta Crystallogr. A 2007, 64(1), 112-122.
https://doi.org/10.1107/S0108767307043930
[13]. Sheldrick, G. M. Acta Crystallogr. C 2015, 71(1), 3-8.
https://doi.org/10.1107/S2053273314026370
[14]. Sheldrick, G. M. Acta Crystallogr. A 2015, 71(1), 3-8.
https://doi.org/10.1107/S2053273314026370
[15]. Spek, A. L. Acta Crystallogr. C 2015, 71(1), 9-18.
https://doi.org/10.1107/S2053229614024929
[16]. Dolomanov, O. V.; Bourhis, L. J.; Gildea, R. J.; Howard, J. A. K.; Puschmann, H. J. Appl. Cryst. 2009, 42(2), 339-341.
https://doi.org/10.1107/S0021889808042726
[17]. Macrae, C. F.; Bruno, I. J.; Chisholm, J. A.; Edgington, P. R.; McCabe, P.; Pidcock, E.; Rodriguez-Monge, L.; Taylor, R.; van de Streek, J.; Wood, P. A. J. Appl. Cryst. 2008, 41(2), 466-470.
https://doi.org/10.1107/S0021889807067908
[18]. Rajput, J. D. Med. Chem. (Los Angeles) 2016, 6(2), 123-128.
[19]. Bagul, S. D.; Rajput, J. D.; Tadavi, S. K.; Bendre, R. S. Res. Chem. Intermed. 2016, 43(4), 2241-2252.
https://doi.org/10.1007/s11164-016-2759-5
[20]. Rajput, J. D.; Bagul, S. D.; Hosamani, A. A.; Patil, M. M.; Bendre, R. S. Res. Chem. Intermed. 2017, 43(10), 5377-5393.
https://doi.org/10.1007/s11164-017-2933-4
[21]. Rajput, J. D.; Bagul, S. D.; Bendre, R. S. Res. Chem. Intermed. 2017, 43(11), 6601-6616.
https://doi.org/10.1007/s11164-017-3007-3
[22]. Kavitha, P.; Laxma Reddy, K. Arabian J. Chem. 2016, 9(5), 640-648.
https://doi.org/10.1016/j.arabjc.2013.06.018
[23]. Ozyanik, M.; Demirci, S.; Bektas, H.; Demirbas, N.; Demirbas, A.; Karaoglu, S. A. Turk. J. Chem. 2012, 36, 233-246.
[24]. Shanker, K.; Robini, R.; Shravankumar, K.; Roddy, P. M.; Ho, Y. P.; Ravlnder, V. J. Indian Chem. Soc. 2009, 86, 153-161.
[25]. Budige, G.; Puchakayala, M. R.; Kongara, S. R.; Hu, A.; Vadde, R. Chem. Pharm. Bull. 2011, 59(2), 166-171.
https://doi.org/10.1248/cpb.59.166
[26]. Tadavi, S. K.; Yadav, A. A.; Bendre, R. S. J. Mol. Struc. 2018, 1152, 223-231.
https://doi.org/10.1016/j.molstruc.2017.09.112
[27]. Ali, O. A. M. Spectrochim. Acta A 2014, 132, 52-60.
https://doi.org/10.1016/j.saa.2014.03.127
[28]. Geeta, B.; Shravankumar, K.; Reddy, P. M.; Ravikrishna, E.; Sarangapani, M.; Reddy, K. K.; Ravinder, V. Spectrochim. Acta A 2010, 77(4), 911-915.
https://doi.org/10.1016/j.saa.2010.08.004
[29]. Coombs, R. R.; Ringer, M. K.; Blacquiere, J. M.; Smith, J. C.; Neilsen, J. Scott.; Uh, Y.-S.; Gilbert, J. Bryson.; Leger, L. J.; Zhang, H.; Irving, A. M.; Wheaton, S. L.; Vogels, C. M.; Westcott, S. A.; Decken, A.; Baerlocher, F. J. Transition Met. Chem. 2005, 30(4), 411-418.
https://doi.org/10.1007/s11243-004-7625-4
[30]. Allen, F. H.; Kennard, O.; Watson, D. G.; Brammer, L.; Orpen, A. G.; Taylor, R. J. Chem. Soc., Perkin Trans. 2 1987, 12, S1-S19.
https://doi.org/10.1039/p298700000s1
[31]. Akbari, A.; Ahmadi, M.; Takjoo, R.; Heinemann, F. W. J. Coord. Chem. 2013, 66(11), 1866-1875.
https://doi.org/10.1080/00958972.2013.792334
[32]. Gao, E. J.; Zhu, M. C.; Huang, Y.; Liu, L.; Liu, H. Y.; Liu, F. C.; Ma, S.; Shi, C. Y. Eur. J. Med. Chem. 2010, 45(3), 1034-1041.
https://doi.org/10.1016/j.ejmech.2009.11.048
[33]. Tweedy, B. G. Phytopathology 1964, 55, 910-914.
[34]. Dharmaraj, N.; Viswanathamurthi, P.; Natarajan, K. Transition Met. Chem. 2001, 26(1/2), 105-109.
https://doi.org/10.1023/A:1007132408648
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DOI Link: https://doi.org/10.5155/eurjchem.11.4.377-384.2040

















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