European Journal of Chemistry 2010, 1(4), 322-324 | doi: https://doi.org/10.5155/eurjchem.1.4.322-324.65 | Get rights and content

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Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives


Sattar Ebrahimi (1,*)

(1) Department of Chemistry, Islamic Azad University, Malayer Branch, IR-65718-117, Iran
(*) Corresponding Author

Received: 16 Apr 2010 | Revised: 13 Aug 2010 | Accepted: 26 Sep 2010 | Published: 22 Dec 2010 | Issue Date: December 2010

Abstract


New 1,2,4-triazoles (4a-c), 1,3,4-thiadiazoles (5a-c) and 1,3,4-oxadiazoles (6a-c) containing isomeric pyridyl and cyclohexyl were synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides (3a-c) in alkaline media, acid and neutral condition respectively. The chemical structures of newly synthesized compounds were established with help of FT-IR, 1H-NMR and mass spectral data.

1_4_322_324_800


Keywords


1,2,4-Triazole; 1,3,4-Thiadiazole; 1,3,4-Oxadiazole; Thiosemicarbazide

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DOI: 10.5155/eurjchem.1.4.322-324.65

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[2]. Mashooq Ahmad Bhat, Mohamed A. Al-Omar, Ahmed M. Naglah, Mohamed M. Abdulla, Hoong-Kun Fun
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DOI: 10.1007/s00044-014-1216-5
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[3]. Qiaoling Liu, Huizhi Du, Xiaoze Ren, Wei Bian, Li Fan, Shaomin Shuang, Chuan Dong, Qin Hu, Martin M. F. Choi
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How to cite


Ebrahimi, S. Eur. J. Chem. 2010, 1(4), 322-324. doi:10.5155/eurjchem.1.4.322-324.65
Ebrahimi, S. Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives. Eur. J. Chem. 2010, 1(4), 322-324. doi:10.5155/eurjchem.1.4.322-324.65
Ebrahimi, S. (2010). Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives. European Journal of Chemistry, 1(4), 322-324. doi:10.5155/eurjchem.1.4.322-324.65
Ebrahimi, Sattar. "Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives." European Journal of Chemistry [Online], 1.4 (2010): 322-324. Web. 24 Sep. 2021
Ebrahimi, Sattar. "Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives" European Journal of Chemistry [Online], Volume 1 Number 4 (22 December 2010)

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