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Synthesis of some novel Schiff bases containing 1,2,4-triazole ring
Akbar Mobinikhaledi (1,*)
, Naser Foroughifar (2) , Mansooreh Khanpour (3) , Sattar Ebrahimi (4) (1) Department of Chemistry, Faculty of Sciences, Arak University, Arak, IR-38156, Iran
(2) Department of Chemistry, Faculty of Sciences, Arak University, Arak, IR-38156, Iran
(3) Department of Chemistry, Faculty of Sciences, Arak University, Arak, IR-38156, Iran
(4) Department of Chemistry, Faculty of Sciences, Arak University, Arak, IR-38156, Iran
(*) Corresponding Author
Received: 24 Mar 2010 | Accepted: 24 Mar 2010 | Published: 31 Mar 2010 | Issue Date: March 2010
Abstract
4-Allyl-5-piridine-4-yl-4H-1,2,4-triazole-3-thiol was prepared under facile condition via the formation of 2-isonicotinoyl-N-allylhydrazinecarbothioamide. In addition, ethyl[(4-allyl-5-pyridine-4-yl-4H-1¸2¸4-triazole-3-yl)thio]acetate was synthesized via the reaction of 4-allyl-5-piridine-4-yl-4H-1,2,4-triazole-3-thiol with ethyl chloroacetate. 2-[(4-Allyl-5-pyridine-4-yl-4H-1,2,4-triazole-3-yl)thio]acetohydrazide obtained by using ethyl[(4-allyl-5-pyridine-4-yl-4H-1¸2¸4-triazole-3-yl)thio]acetate as a precursor by two steps, was converted to Schiff base derivatives, 6a-j. All synthesized compounds were characterized by elemental analyses, IR spectroscopy, 1H NMR and 13C NMR spectroscopy. The cis/trans conformers of E isomer were present in DMSO solution of compounds 6a-j.
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DOI: 10.5155/eurjchem.1.1.33-36.5
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Research Council of Arak University
Citations
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DOI Link: https://doi.org/10.5155/eurjchem.1.1.33-36.5
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