

Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives
Ahmed Mutanabbi Abdula (1,*)

(1) Chemistry Department, College of Science, Al-Mustansiriyah University, Baghdad, 00964, Iraq
(*) Corresponding Author
Received: 23 Mar 2013 | Revised: 23 Apr 2013 | Accepted: 23 Apr 2013 | Published: 30 Sep 2013 | Issue Date: September 2013
Abstract
(E)-Chalcone derivatives were synthesized by the Claisen-Schmidt condensation of aromatic aldehydes with methyl ketones. 5-Arylfuran-2-carboxaldehydes (1a-b) were synthesized by Meerwein´s method and condensed with 2-acetylpyrole or 2-acetylfuran to produce the new chalcone derivatives (2a-d). The new chalcones were characterized using FT-IR and GC-MS. The synthesized compounds were also screened against some bacterial species to evaluate their activity as promising antibacterial agents.

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DOI: 10.5155/eurjchem.4.3.207-210.780
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Chemistry Department, College of Science, Al-Mustansiriyah University, Baghdad, Iraq
Citations
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Chemical Data Collections 28, 100423, 2020
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