European Journal of Chemistry 2013, 4(3), 207-210 | doi: | Get rights and content


Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives

Ahmed Mutanabbi Abdula (1,*)

(1) Chemistry Department, College of Science, Al-Mustansiriyah University, Baghdad, 00964, Iraq
(*) Corresponding Author

Received: 23 Mar 2013 | Revised: 23 Apr 2013 | Accepted: 23 Apr 2013 | Published: 30 Sep 2013 | Issue Date: September 2013


(E)-Chalcone derivatives were synthesized by the Claisen-Schmidt condensation of aromatic aldehydes with methyl ketones. 5-Arylfuran-2-carboxaldehydes (1a-b) were synthesized by Meerwein´s method and condensed with 2-acetylpyrole or 2-acetylfuran to produce the new chalcone derivatives (2a-d). The new chalcones were characterized using FT-IR and GC-MS. The synthesized compounds were also screened against some bacterial species to evaluate their activity as promising antibacterial agents.



Furan derivatives; Meerwein's reaction; Chalcone derivatives; Antibacterial activity; Claisen-Schmidt condensation; 1,3-Diphenyl-2-propen-1-ones

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DOI: 10.5155/eurjchem.4.3.207-210.780

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Chemistry Department, College of Science, Al-Mustansiriyah University, Baghdad, Iraq



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How to cite

Abdula, A. Eur. J. Chem. 2013, 4(3), 207-210. doi:10.5155/eurjchem.4.3.207-210.780
Abdula, A. Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives. Eur. J. Chem. 2013, 4(3), 207-210. doi:10.5155/eurjchem.4.3.207-210.780
Abdula, A. (2013). Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives. European Journal of Chemistry, 4(3), 207-210. doi:10.5155/eurjchem.4.3.207-210.780
Abdula, Ahmed. "Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives." European Journal of Chemistry [Online], 4.3 (2013): 207-210. Web. 27 May. 2020
Abdula, Ahmed. "Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives" European Journal of Chemistry [Online], Volume 4 Number 3 (30 September 2013)

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