European Journal of Chemistry

Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives



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Ahmed Mutanabbi Abdula

Abstract

(E)-Chalcone derivatives were synthesized by the Claisen-Schmidt condensation of aromatic aldehydes with methyl ketones. 5-Arylfuran-2-carboxaldehydes (1a-b) were synthesized by Meerwein´s method and condensed with 2-acetylpyrole or 2-acetylfuran to produce the new chalcone derivatives (2a-d). The new chalcones were characterized using FT-IR and GC-MS. The synthesized compounds were also screened against some bacterial species to evaluate their activity as promising antibacterial agents.

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Abdula, A. M. Synthesis, Characterization and Antibacterial Activity of (E)-Chalcone Derivatives. Eur. J. Chem. 2013, 4, 207-210.

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Chemistry Department, College of Science, Al-Mustansiriyah University, Baghdad, Iraq
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