European Journal of Chemistry 2013, 4(3), 235-239 | doi: https://doi.org/10.5155/eurjchem.4.3.235-239.782 | Get rights and content

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Synthesis and characterization of diaza analogues of podophyllotoxin


Yeriyur Basavaiah Basavaraju (1,*) , Basavaiah Umesha (2)

(1) Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570006, Karnataka, India
(2) Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570006, Karnataka, India
(*) Corresponding Author

Received: 23 Mar 2013 | Accepted: 07 May 2013 | Published: 30 Sep 2013 | Issue Date: September 2013

Abstract


In an attempt to synthesize the novel diaza analogues of podophyllotoxin (7a-d) in five step reactions. The synthesis of title compounds has been achieved from tetralones, which were formylated with ethylformate; prepared via cyclization with hydrazine hydrate. Furthermore, these newly synthesized compounds were characterized by spectral and elemental analysis data.

4_3_235_239

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European Journal of Chemistry

Keywords


Chalcones; Tetralones; Ethylformate; Sodium hydride; Hydrazine hydrate; Cyclopropyl ketones

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DOI: 10.5155/eurjchem.4.3.235-239.782

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Funding information


Indian Institute of Technology, Bombay, India

Citations

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[1]. Basavaiah Umesha, Yeriyur Basavaiah Basavaraju, Manpreet Kaur, Hemmige S. Yathirajan, Jerry P. Jasinski
1-(3,4-Dimethoxyphenyl)-3-phenylprop-2-en-1-one
Acta Crystallographica Section E Structure Reports Online  70(3), o368, 2014
DOI: 10.1107/S160053681400378X
/


[2]. Krishna Mudeenahally Hucchegowda, Basavaraju Yeriyur Basavaiah, Umesha Basavaiah, Shivakumar Santhekasalagere Basavaiah
Synthesis and study of antimicrobial activity of new tetralone esters
European Journal of Chemistry  5(4), 584, 2014
DOI: 10.5155/eurjchem.5.4.584-587.1093
/


[3]. Kanakapura Narayanaramakrishna Padmavath, Yeriyuru Basavaiah Basavaraju, Basavaiah Umesha
Synthesis and characterization of tetralones as intermediates for podophyllotoxin analogues
European Journal of Chemistry  7(2), 192, 2016
DOI: 10.5155/eurjchem.7.2.192-194.1389
/


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How to cite


Basavaraju, Y.; Umesha, B. Eur. J. Chem. 2013, 4(3), 235-239. doi:10.5155/eurjchem.4.3.235-239.782
Basavaraju, Y.; Umesha, B. Synthesis and characterization of diaza analogues of podophyllotoxin. Eur. J. Chem. 2013, 4(3), 235-239. doi:10.5155/eurjchem.4.3.235-239.782
Basavaraju, Y., & Umesha, B. (2013). Synthesis and characterization of diaza analogues of podophyllotoxin. European Journal of Chemistry, 4(3), 235-239. doi:10.5155/eurjchem.4.3.235-239.782
Basavaraju, Yeriyur, & Basavaiah Umesha. "Synthesis and characterization of diaza analogues of podophyllotoxin." European Journal of Chemistry [Online], 4.3 (2013): 235-239. Web. 3 Jun. 2023
Basavaraju, Yeriyur, AND Umesha, Basavaiah. "Synthesis and characterization of diaza analogues of podophyllotoxin" European Journal of Chemistry [Online], Volume 4 Number 3 (30 September 2013)

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