European Journal of Chemistry 2014, 5(1), 133-137 | doi: https://doi.org/10.5155/eurjchem.5.1.133-137.923 | Get rights and content

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Microwave assisted synthesis of 2-amino-6-methoxy-4H-benzo[h]chromene derivatives


Ahmed Mohamed El-Agrody (1,*) , Al-Anood Mohamed Al-Dies (2) , Ahmed Mahmoud Fouda (3)

(1) Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt
(2) Chemistry Department, Faculty of Science, King Khalid University, Abha, 61413, Saudi Arabia
(3) Chemistry Department, Faculty of Science, King Khalid University, Abha, 61413, Saudi Arabia
(*) Corresponding Author

Received: 10 Sep 2013 | Accepted: 13 Oct 2013 | Published: 31 Mar 2014 | Issue Date: March 2014

Abstract


A convenient and efficient method using microwave assisted synthesis of 4H-benzo[h]chromenes (7 and 8), by the reaction of 4-methoxy-1-naphthol (1) with a mixture of aromatic aldehydes (2) and malononitrile (3) or ethyl cyanoacetate (5) and also, by the reaction of 4-methoxy-1-naphthol (1) with α-cyanocinnamonitriles (4) or ethyl α-cyanocinnamates (6) in ethanolic piperidine solution was examined. Structures of the newly synthesized compounds were established on the basis of spectral data, IR, 1H NMR, 13C NMR, 13C NMR-DEPT and MS data.


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Keywords


Benzochromenes; Pyran derivatives; Microwave synthesis; 4-Methoxy-1-naphthol; α-Cyanocinnamonitriles; Ethyl α-cyanocinnamates

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DOI: 10.5155/eurjchem.5.1.133-137.923

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King Abdulaziz City for Science and Technology (KACST)

Citations

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[1]. Fawzia F. Alblewi, Rawda M. Okasha, Zainab M. Hritani, Hany M. Mohamed, Mohammed A.A. El-Nassag, Ahmed H. Halawa, Ahmed Mora, Ahmed M. Fouda, Mohammed A. Assiri, Al-Anood M. Al-Dies, Tarek H. Afifi, Ahmed M. El-Agrody
Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene
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DOI: 10.1016/j.bioorg.2019.03.059
/


[2]. Heba K.A. El-Mawgoud, Ahmed M. Fouda, Mohammed A.A. El-Nassag, Ahmed A. Elhenawy, Mohammed Y. Alshahrani, Ahmed M. El-Agrody
Discovery of novel rigid analogs of 2-naphthol with potent anticancer activity through multi-target topoisomerase I & II and tyrosine kinase receptor EGFR & VEGFR-2 inhibition mechanism
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DOI: 10.1016/j.cbi.2022.109838
/


[3]. Ahmed M. Fouda, Mohammed A. Assiri, Ahmed Mora, Tarik E. Ali, Tarek H. Afifi, Ahmed M. El-Agrody
Microwave synthesis of novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]chromene moieties: Induces cell cycle arrest and apoptosis in human cancer cells via dual inhibition of topoisomerase I and II
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DOI: 10.1016/j.bioorg.2019.103289
/


[4]. Fawzia Alblewi, Rawda Okasha, Areej Eskandrani, Tarek Afifi, Hany Mohamed, Ahmed Halawa, Ahmed Fouda, Al-Anood Al-Dies, Ahmed Mora, Ahmed El-Agrody
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DOI: 10.3390/molecules24061060
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[5]. Ahmed M. Fouda, Mohammed A.A. El-Nassag, Ahmed A. Elhenawy, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Mohammed M. Alam, Ahmed M. El-Agrody
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DOI: 10.1016/j.molstruc.2021.131555
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[6]. Shivaputra A Patil, Siddappa A Patil, Renukadevi Patil
Microwave-assisted synthesis of chromenes: biological and chemical importance
Future Medicinal Chemistry  7(7), 893, 2015
DOI: 10.4155/fmc.15.38
/


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DOI: 10.3390/cryst12070982
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[8]. Ahmed M. Fouda, Ahmed H. Hassan, Essam M. Eliwa, Hany E.A. Ahmed, Al-Anood M. Al-Dies, Abdelsattar M. Omar, Hesham S. Nassar, Ahmed H. Halawa, Naif Aljuhani, Ahmed M. El-Agrody
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DOI: 10.1016/j.bioorg.2020.104387
/


[9]. Ahmed M. El-Agrody, Ahmed H. Halawa, Ahmed M. Fouda, Al-Anood M. Al-Dies
The anti-proliferative activity of novel 4H-benzo[h]chromenes, 7H-benzo[h]-chromeno[2,3-d]pyrimidines and the structure–activity relationships of the 2-, 3-positions and fused rings at the 2, 3-positions
Journal of Saudi Chemical Society  21(1), 82, 2017
DOI: 10.1016/j.jscs.2016.03.002
/


[10]. Rawda Okasha, Fawzia Albalawi, Tarek Afifi, Ahmed Fouda, Al-Anood Al-Dies, Ahmed El-Agrody
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DOI: 10.3390/molecules21111450
/


[11]. Tarek H. Afifi, Sayed M. Riyadh, Anwar A. Deawaly, Arshi Naqvi
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DOI: 10.1007/s00044-019-02387-5
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[12]. Hany E.A. Ahmed, Mohammed A.A. El-Nassag, Ahmed H. Hassan, Hany M. Mohamed, Ahmed H. Halawa, Rawda M. Okasha, Saleh Ihmaid, Shimaa Mohamed Abd El-Gilil, Essam S.A.E.H. Khattab, Ahmed M. Fouda, Ahmed M. El-Agrody, Ateyatallah Aljuhani, Tarek H. Afifi
Developing lipophilic aromatic halogenated fused systems with specific ring orientations, leading to potent anticancer analogs and targeting the c-Src Kinase enzyme
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DOI: 10.1016/j.molstruc.2019.03.012
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[13]. Alaa S. Abd-El-Aziz, Azhaar Alsaggaf, Eman Assirey, Arshi Naqvi, Rawda M. Okasha, Tarek H. Afifi, Mohamed Hagar
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DOI: 10.3390/ijms22062807
/


[14]. Ayman M. S. Youssef, Ahmed M. Fouda, Rasha M. Faty
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DOI: 10.1186/s13065-018-0419-0
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[15]. Xinwei He, Ruxue Li, Pui Ying Choy, Jiahui Duan, Zhenzhen Yin, Keke Xu, Qiang Tang, Rong-Lin Zhong, Yongjia Shang, Fuk Yee Kwong
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[16]. Ivan N. Bardasov, Anastasiya U. Alekseeva, Denis L. Mihailov, Oleg V. Ershov, Dmitry A. Grishanov
Double heteroannulation reactions of 1-naphthol with alkyl- and arylmethylidene derivatives of malononitrile dimer
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DOI: 10.1016/j.tetlet.2015.02.081
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[17]. Subrahmanya Ishwar Bhat
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[18]. Ahmed M. Fouda, Ahmad Irfan, Abdullah G. Al-Sehemi, Ahmed M. El-Agrody
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DOI: 10.1016/j.molstruc.2021.130542
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[19]. Ahmed M. El-Agrody, Ahmed M. Fouda, Hany M. Mohamed, Mohammed Y. Alshahrani, Hazem A. Ghabbour, Abd El-Galil E. Amr, Rawda M. Okasha, Ahmed M. Naglah, Abdulrahman A. Almehizia, Ahmed A. Elhenawy
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DOI: 10.3390/cryst12050737
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[20]. Ahmed M. El-Agrody, Ahmed M. Fouda, Al-Anood M. Al-Dies
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DOI: 10.1007/s00044-013-0904-x
/


References


[1]. Kumar, D.; Buchi Reddy, V.; Sharad, S.; Dube, U.; Kapur, S. Eur. J. Med. Chem. 2009, 44, 3805-3809.
http://dx.doi.org/10.1016/j.ejmech.2009.04.017

[2]. Jeso, V.; Nicolaou, K. C. Tetrahedron Lett, 2009, 50, 1161-1163.
http://dx.doi.org/10.1016/j.tetlet.2008.12.096

[3]. Alvey, L.; Prado, S.; Saint-Joanis, B.; Michel, S.; Koch, M.; Cole, S. T.; Tillequin, F.; Janin, Y. L. Eur. J. Med. Chem. 2009, 44, 2497-2505.
http://dx.doi.org/10.1016/j.ejmech.2009.01.017

[4]. Raj, T.; Kaur, B. R.; Kumar, S. R.; Gupta, V.; Sharma, D.; Paul, S. I. M. Eur. J. Med. Chem. 2009, 44, 3209-3216.
http://dx.doi.org/10.1016/j.ejmech.2009.03.030

[5]. Kidwai, M.; Poddar, R.; Bhardwaj, S.; Singh, S.; Mehta, L. P. Eur. J. Med. Chem. 2010, 45, 5031-5038.
http://dx.doi.org/10.1016/j.ejmech.2010.08.010

[6]. DaSilva, D. B.; Tulli, E. C. O.; Militao, G. C. G.; Costa-Lotufo, L. V.; Pessoa, C.; DeMoraes, M. O.; Albuquerque S.; DeSiqueira, J. M. Phytomedicine 2009, 70, 590-595.

[7]. Tanaka, J. C. A.; Da Silva, C. C.; Ferreira, I. C. P.; Machado, G. M. C.; Leon L. L.; De Oliveira, A. J. B. Phytomedicine 2007, 14, 377-380.
http://dx.doi.org/10.1016/j.phymed.2006.09.002

[8]. Lakshmi, V.; Pandey, K.; Kapil, A.; Singh, N.; Samant M.; Dube, A. Phytomedicine 2007, 14, 36-42.
http://dx.doi.org/10.1016/j.phymed.2005.10.002

[9]. Torres-Santos, E. C.; Lopes, D.; Rodriguez, R.; Oliveira, J. P.; Carauta, P.; Bandeira Falcao, C. A.; Kaplan, M. A. C.; Rossi-Bergmann, B. Phytomedicine 2004, 11, 114-120.
http://dx.doi.org/10.1078/0944-7113-00381

[10]. Sabry, N. M.; Mohamed, H. M.; Khattab, E. S. A. E. H.; Motlaq, S. S.; El-Agrody, A. M. Eur. J. Med. Chem. 2011, 46, 765-772.
http://dx.doi.org/10.1016/j.ejmech.2010.12.015

[11]. Rampa, A.; Bisi, A.; Belluti, F.; Gobbi, S.; Piazzi, L.; Valenti, P.; Zampiron, A.; Caputo, A.; Varani, K.; Borea, P. A.; Carrara, M. Il Farmaco 2005, 60, 135-147.
http://dx.doi.org/10.1016/j.farmac.2004.09.006

[12]. Alvey, L.; Prado, S.; Huteau, V.; Saint-Joanis, B.; Michel, S.; Koch, M.; Cole, S. T.; Tillequin F.; Janin, Y. L. Bioorg. Med. Chem. 2008, 16, 8264-8272.
http://dx.doi.org/10.1016/j.bmc.2008.06.057

[13]. Symeonidis, T.; Chamilos, M.; Hadjipavlou-Litina, D. J.; Kallitsakis, M.; Litinas, K. E. Bioorg. Med. Chem. Lett. 2009, 19, 1139-1142.
http://dx.doi.org/10.1016/j.bmcl.2008.12.098

[14]. Singh, O. M.; Devi, N. S.; Thokchom, D. S.; Sharma, G. J. Eur. J. Med. Chem. 2010, 45, 2250-2257.
http://dx.doi.org/10.1016/j.ejmech.2010.01.070

[15]. Vukovic, N.; Sukdolak, S.; Solujic, S.; Niciforovic, N. Food Chem. 2010, 120, 1011-1018.
http://dx.doi.org/10.1016/j.foodchem.2009.11.040

[16]. Tandon, V. K.; Vaish, M.; Jain, S.; Bhakuni, D. S.; Srimal, R. C. Indian J. Pharm. Sci. 1991, 53, 22-27.

[17]. Magedov, I. V.; Manpadi, M.; Evdokimov, N. M.; Elias, E. M.; Rozhkova, E.; Ogasawara, M. A.; Bettale, J. D.; Przhevalskii, N. M.; Rogelj, S.; Kornienko, A. Bioorg. Med. Chem. Lett. 2007, 17, 3872-3876.
http://dx.doi.org/10.1016/j.bmcl.2007.05.004

[18]. Doshi, J. M.; Tian, D.; Xing, C. J. Med. Chem. 2006, 49, 7731-7739.
http://dx.doi.org/10.1021/jm060968r

[19]. Kessel, D.; Reiners, J. J.; Hazeldine, S. T.; Polin, L.; Horwitz, J. P. Mol. Cancer Ther. 2007, 6, 370-379.
http://dx.doi.org/10.1158/1535-7163.MCT-05-0386

[20]. Kemnitzer, W.; Drewe, J.; Jiang, S.; Zhang, H.; Zhao, J.; Crogan-Grundy, C.; Xu, L.; Lamothe, S.; Gourdeau, H.; Denis, R.; Tseng, B.; Kasibhatla, S.; Cai, S. X. J. Med. Chem. 2007, 50, 2858-2864.
http://dx.doi.org/10.1021/jm070216c

[21]. Han, Q. B.; Yang, N. Y.; Tian, H. L.; Qiao, C. F.; Song, J. Z.; Chang, D. C.; Chen, S. L.; Luo, K. Q.; Xu, H. X. Phytochemistry 2008, 69, 2187-2197.
http://dx.doi.org/10.1016/j.phytochem.2008.05.019

[22]. Kemnitzer, W.; Drewe, J.; Jiang, S.; Zhang, H.; Crogan-Grundy, C.; Labrecque, D.; Bubenick, M.; Attardo, G.; Denis, R.; Lamothe, S.; Gourdeau, H.; Tseng, B.; Kasibhatla, S.; Cai, S. X. J. Med. Chem. 2008, 51, 417-423.
http://dx.doi.org/10.1021/jm7010657

[23]. Kemnitzer, W.; Jiang, S.; Wang, Y.; Kasibhatla, S.; Crogan-Grundy, C.; Bubenick, M.; Labrecque, D.; Denis, R.; Lamothe, S.; Attardo, G.; Gourdeau, H.; Tseng, B.; Drewe, J.; Cai, S. X. Bioorg. Med. Chem. Lett. 2008, 18, 603-607.
http://dx.doi.org/10.1016/j.bmcl.2007.11.078

[24]. Huang, W.; Ding, Y.; Miao, Y.; Liu, M. Z.; Li, Y.; Yang, G. F. Eur. J. Med. Chem. 2009, 44, 3687-3696.
http://dx.doi.org/10.1016/j.ejmech.2009.04.004

[25]. Mahmoodi, M.; Aliabadi, A.; Emami, S.; Safavi, M.; Rajabalian, S.; Mohagheghi, M. A.; Khoshzaban, A.; Samzadeh-Kermani, A.; Lamei, N.; Shafiee, A.; Foroumadi, A. Arch. Pharm. Chem. 2010, 343, 411-416.
http://dx.doi.org/10.1002/ardp.200900198

[26]. Endo, S.; Matsunaga, T.; Kuwata, K.; Zhao, H. T.; El-Kabbani, O.; Kitade, Y.; Hara, A. Bioorg. Med. Chem. 2010, 18, 2485-2490.
http://dx.doi.org/10.1016/j.bmc.2010.02.050

[27]. Tseng, T. H.; Chuang, S. K.; Hu, C. C.; Chang, C. F.; Huang, Y. C.; Lin, C. W.; Lee, Y. J. Tetrahedron 2010, 66, 1335-1340.
http://dx.doi.org/10.1016/j.tet.2009.12.002

[28]. Bruhlmann, C.; Ooms, F.; Carrupt, P.; Testa, B.; Catto, M.; Leonetti, F.; Altomare, C.; Cartti, A. J. Med. Chem. 2001, 44, 3195-3198.
http://dx.doi.org/10.1021/jm010894d

[29]. Kesten, S. R.; Heffner, T. G.; Johnson, S. J.; Pugsley, T. A.; Wright, J. L.; Wise, D. L. J. Med. Chem. 1999, 42, 3718-3725.
http://dx.doi.org/10.1021/jm990266k

[30]. Lee, K. S.; Khil, L. Y.; Chae, S. H.; Kim, D.; Lee, B. H.; Hwang, G. S.; Moon, C. H.; Chang, T. S.; Moon, C. K. Life Sci. 2006, 78, 1091-1097.
http://dx.doi.org/10.1016/j.lfs.2005.06.017

[31]. Coudert, P.; Coyquelet, J. M.; Bastide, J.; Marion Y.; Fialip, J. Ann. Pharm. Fr. 1988, 46, 91-96.

[32]. Gajbhiye, A.; Mallareddy, V.; Achaiah, G. Indian J. Pharm. Sci. 2008, 70, 118-120.
http://dx.doi.org/10.4103/0250-474X.44589

[33]. Ghate, M.; Kusanur, R. A.; Kulkarni, M. V. Eur. J. Med. Chem. 2005, 40, 882-887.
http://dx.doi.org/10.1016/j.ejmech.2005.03.025

[34]. El-Sayed, A. T.; Ibrahim, M. A. J. Braz. Chem. 2010, 21, 1007-1016.
http://dx.doi.org/10.1590/S0103-50532010000600010

[35]. Amin, K. M.; Kamel, M. M.; Anwar, M. M.; Khedr M.; Syam, Y. M. Eur. J. Med. Chem. 2010, 45, 2117-2131.
http://dx.doi.org/10.1016/j.ejmech.2009.12.078

[36]. Keri, R. S.; Hosamani, K. M.; Shingalapur, R. V.; Hugar, M. H. Eur. J. Med. Chem. 2010, 45, 2597-2605.
http://dx.doi.org/10.1016/j.ejmech.2010.02.048

[37]. Sashidhara, K. V.; Kumar, M.; Modukuri, R. K.; Srivastava, A.; Puri, A. Bioorg. Med. Chem. Lett. 2011, 21, 6709-6713.
http://dx.doi.org/10.1016/j.bmcl.2011.09.053

[38]. Hiramoto, K.; Nasuhara, A.; Michiloshi, K.; Kato, T.; Kikugawa, K. Mutation Res. 1997, 395, 47-56.
http://dx.doi.org/10.1016/S1383-5718(97)00141-1

[39]. Yavari, I.; Djahaniani, H.; Nasiri, F. Synthesis 2004, 679-682.
http://dx.doi.org/10.1055/s-2004-815990

[40]. Yavari, I.; Djahaniani, H.; Nasiri, F. Tetrahedron 2003, 59, 9409-9412.
http://dx.doi.org/10.1016/j.tet.2003.09.072

[41]. Gong, K.; Wang, H. L.; Fang, D.; Liu, Z. L. Catal. Commun. 2008, 9, 650-563.
http://dx.doi.org/10.1016/j.catcom.2007.07.010

[42]. Abd-El-Aziz, A. S.; El-Agrody, A. M.; Bedair, A. H.; Corkery, T. C.; Ata, A. Heterocycles 2004, 63, 1793-1312.
http://dx.doi.org/10.3987/COM-04-10089

[43]. Kemnitzer, W.; Kasibhatla, S.; Jiang, S.; Zhang, H.; Zhao, J.; Lia, S.; Xu, L.; Crogan-Grundy, C.; Denis, R.; Barriault, N.; Villacourt, L.; Charron, S.; Dodd, J.; Attardo, G.; Labrique, D.; Lamothe, S.; Gourdeau, H.; Tseng, B.; Drewe, J.; Cia, S. X. Bioorg. Med. Chem. Lett. 2005, 15, 4745-4751.
http://dx.doi.org/10.1016/j.bmcl.2005.07.066

[44]. Kemnitzer, W.; Drewe, J.; Jiang, S.; Zhang, H.; Wang, W.; Lia, S.; Xu, L.; Crogan-Grundy, C.; Denis, R.; Barriault, N.; Villacourt, L.; Charron, S.; Dodd, J.; Attardo, G.; Labrique, D.; Lamothe, S.; Gourdeau, H.; Tseng, B.; Drewe, J.; Cia, S. X. J. Med. Chem. 2004, 47, 6299-6310.
http://dx.doi.org/10.1021/jm049640t

[45]. Dyachenko, V. D.; Chernega, A. N. Russ. J. Org. Chem. 2006, 42, 567-576.
http://dx.doi.org/10.1134/S1070428006040142

[46]. Ballini, R.; Bosica, G.; Conforti, M. L.; Maggi, R.; Mazzacanni, A.; Righi, P.; Sartori, G. Tetrahedron 2001, 57, 1395-1398.
http://dx.doi.org/10.1016/S0040-4020(00)01121-2

[47]. Jin, T. S.; Xiao, J. C.; Wang S. J.; Li, T. S. Ultrson. Sonochem. 2004, 11, 393-397.

[48]. Du, Z.; Siau, W. Y.; Wang, J. Tetrahedron Lett. 2011, 52, 6137-6141.
http://dx.doi.org/10.1016/j.tetlet.2011.09.030

[49]. Radomkit, S.; Sarnpitak, P.; Tummatorn, J.; Batsomboon, P.; Ruchirawat, S.; Ploypradith, P. Tetrahedron 2011, 67, 3904-3914.
http://dx.doi.org/10.1016/j.tet.2011.03.059

[50]. Maggi, R.; Ballini, R.; Sartori, G.; Sartorio, R. Tetrahedron Lett. 2004, 45, 2297-2299.
http://dx.doi.org/10.1016/j.tetlet.2004.01.115

[51]. Kappe, C. O. Angew. Chem. Int. Ed. 2004, 43, 6250-6284.
http://dx.doi.org/10.1002/anie.200400655

[52]. Bose, A. K.; Manhas, M. S.; Ganguly, S. N.; Sharma, A. H.; Banik, B. K. Synthesis 2002, 1578-1591.
http://dx.doi.org/10.1055/s-2002-33344

[53]. Varma, R. S. Green Chem. 1999, 1, 43-55.
http://dx.doi.org/10.1039/a808223e

[54]. Shi, L.; Wang, M.; Fan, C. A.; Zhang, F. M.; Tu, Y. Q. Org. Lett. 2003, 5, 3515-3517.
http://dx.doi.org/10.1021/ol0353868

[55]. Shi, L.; Wang, M.; Fan, C. A.; Zhang, F. M.; Tu, Y. Q. Org. Lett. 2004, 6, 1001-1003.
http://dx.doi.org/10.1021/ol049936t

[56]. Wu, X.; Larhed, M. Org. Lett. 2005, 7, 3327-3329.
http://dx.doi.org/10.1021/ol0512031

[57]. Hamelin, J.; Bazureau, J. P.; Texier-Boullet, F., In Microwaves in Organic Synthesis, Ed.: Loupy, A., Wiley-VCH, Weinheim, Germany, 2002, pp. 253.
http://dx.doi.org/10.1002/3527601775.ch8

[58]. Kidwai, M.; Saxena, S.; Khan, M. K. R.; Thukra, S. S. Bioorg. Med. Chem. Lett. 2005, 15, 4295-4298.
http://dx.doi.org/10.1016/j.bmcl.2005.06.041

[59]. Surpur, M. P.; Kshirsagar, S.; Samant, S. D. Tetrahedron Lett. 2009, 50, 719-722.
http://dx.doi.org/10.1016/j.tetlet.2008.11.114

[60]. Mekheimer, R. A.; Sadek, K. U. Chin. Chem. Lett. 2009, 271-274.
http://dx.doi.org/10.1016/j.cclet.2008.11.025

[61]. El-Agrody, A. M. J. Chem. Res. (S) 1994, 280-281.

[62]. El-Agrody, A. M.; Emam, H. A.; El-Hakim, M. H.; Abd El-Latif, M. S.; Fakery, A. H. J. Chem. Res. (S) 1997, 320-321.

[63]. El-Agrody, A. M.; Emam, H. A.; El-Hakim, M. H.; Abd El-Latif, M. S.; Fakery, A. H. J. Chem. Res. (M) 1997, 2039-2048.

[64]. Bedair, A. H.; El-Hady, N. A.; Abd El-Latif, M. S.; Fakery, A. H.; El-Agrody, A. M. Il Farmaco 2000, 55, 708-714.
http://dx.doi.org/10.1016/S0014-827X(00)00097-5

[65]. El-Agrody, A. M.; El-Hakim, M. H.; Abd El-Latif, M. S.; Fakery, A. H.; El-Sayed, E. S. M.; El-Ghareab, K. A. Acta Pharm. 2000, 50, 111-120.

[66]. Sayed, A. Z.; El-Hady, N. A.; El-Agrody, A. M. J. Chem. Res. (S) 2000, 164-166.

[67]. El-Agrody, A. M.; Abd El-Latif, M. S.; El-Hady, N. A.; Fakery, A. H.; Bedair, A. H. Molecules 2000, 6, 519-527.
http://dx.doi.org/10.3390/60600519

[68]. Bedair, A. H.; Emam, H. A.; El-Hady, N. A.; Ahmed, K. A. R.; El-Agrody, A. M. Il Farmaco 2001, 56, 965-973.
http://dx.doi.org/10.1016/S0014-827X(01)01168-5

[69]. El-Agrody, A. M.; Eid, F. A.; Emam, H. A.; Mohamed, H. M.; Bedair, A. H. Z. Naturforsch. Teil B 2002, 57, 579-585.

[70]. Khafagy, M. M.; Abd El-Wahab, A. H. F.; Eid, F. A.; El-Agrody, A. M. Il Farmaco 2002, 57, 715-722.
http://dx.doi.org/10.1016/S0014-827X(02)01263-6

[71]. Eid, F. A.; Bedair, A. H.; Emam, H. A.; Mohamed, H. M.; El-Agrody, A. M. Al-Azhar Bull. Sci. 2003, 14, 311-342.

[72]. Abd-El-Aziz, A. S.; Mohamed, H. M.; Mohammed, S.; Zahid, S.; Ata, A.; Bedair, A. H.; El-Agrody, A. M.; Harvey, P. D. J. Heterocycl. Chem. 2007, 44, 1287-1300.
http://dx.doi.org/10.1002/jhet.5570440610

[73]. El-Agrody, A. M.; Sabry, N. M.; Motlaq, S. S. J. Chem. Res. 2011, 35, 77-83.
http://dx.doi.org/10.3184/174751911X12964930076728

[74]. Al-Dies, Al-Anood M.; Amr, Abdel-Galil E.; El-Agrody, A. M.; Chia, Tze Shyang; Fun, Hoong-Kun Acta Cryst. E 2012, 68, 1934-1935.

[75]. Al-Sehemi, A. G.; Irfan, A.; El-Agrody, A. M. J. Mol. Struct. 2012, 1018, 171-175.
http://dx.doi.org/10.1016/j.molstruc.2012.03.018

[76]. El-Agrody, A. M.; Mohamed, A. A.; Amr, A. E.; Tze, S.; Fun, H. K. Acta Cryst. E 2012, 68, 1803-1804.
http://dx.doi.org/10.1107/S1600536812021939


How to cite


El-Agrody, A.; Al-Dies, A.; Fouda, A. Eur. J. Chem. 2014, 5(1), 133-137. doi:10.5155/eurjchem.5.1.133-137.923
El-Agrody, A.; Al-Dies, A.; Fouda, A. Microwave assisted synthesis of 2-amino-6-methoxy-4H-benzo[h]chromene derivatives. Eur. J. Chem. 2014, 5(1), 133-137. doi:10.5155/eurjchem.5.1.133-137.923
El-Agrody, A., Al-Dies, A., & Fouda, A. (2014). Microwave assisted synthesis of 2-amino-6-methoxy-4H-benzo[h]chromene derivatives. European Journal of Chemistry, 5(1), 133-137. doi:10.5155/eurjchem.5.1.133-137.923
El-Agrody, Ahmed, Al-Anood Mohamed Al-Dies, & Ahmed Mahmoud Fouda. "Microwave assisted synthesis of 2-amino-6-methoxy-4H-benzo[h]chromene derivatives." European Journal of Chemistry [Online], 5.1 (2014): 133-137. Web. 26 Nov. 2022
El-Agrody, Ahmed, Al-Dies, Al-Anood, AND Fouda, Ahmed. "Microwave assisted synthesis of 2-amino-6-methoxy-4H-benzo[h]chromene derivatives" European Journal of Chemistry [Online], Volume 5 Number 1 (31 March 2014)

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