Synthesis, structural elucidation and X-ray crystallographic studies of 1-(3,5-bis(trifluoromethyl)phenyl)-3-(dimethylamino)prop-2-en-1-one

Stability Nongrum; Susma Das; Shikpika Khanikar; Jai Narain Vishwakarma

doi:10.5155/eurjchem.10.4.381-385.1922

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Published: Dec 31, 2019

DOI: https://doi.org/10.5155/eurjchem.10.4.381-385.1922

Keywords:

Enaminones, Acetophenone, Trifluoromethyl, X-ray crystallography, Geometric parameters, N, N-Dimethylformamide dimethyl acetal

Section

Research Article

Issue

Vol. 10 No. 4 (2019): December 2019

Dates

Stability Nongrum

Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India

http://orcid.org/0000-0002-2427-6007

Susma Das

Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India

http://orcid.org/0000-0002-2391-8792

Shikpika Khanikar

Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India

http://orcid.org/0000-0001-9845-2002

Jai Narain Vishwakarma

Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India

http://orcid.org/0000-0001-9068-4554

Abstract

A new enaminone was synthesized by reacting 3,5-bis-(trifluoromethyl)acetophenones and N,N-dimethylformamide dimethyl acetal and its detailed structural and crystalline properties were studied. The crystal data were found to be as C₁₃H₁₁F₆NO, monoclinic, space group P2₁/c (no. 14), a = 8.1556(8) Å, b = 24.877(3) Å, c = 7.6067(7) Å, β = 116.745(6)°, V = 1378.2(3) Å³, Z = 4, T = 293(2) K, μ(MoKα) = 0.150 mm^-1, Dcalc = 1.500 g/cm³, 40777 reflections measured (5.594° ≤ 2Θ ≤ 56.786°), 3413 unique (R_int = 0.1040, R_sigma = 0.0584) which were used in all calculations. The final R₁ was 0.0771 (I > 2σ(I)) and wR₂ was 0.2541 (all data).

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Nongrum, S.; Das, S.; Khanikar, S.; Vishwakarma, J. N. Synthesis, Structural Elucidation and X-Ray Crystallographic Studies of 1-(3,5-bis(trifluoromethyl)phenyl)-3-(dimethylamino)prop-2-En-1-One. Eur. J. Chem. 2019, 10, 381-385.

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