

Synthesis, characterization and acute toxicity of new Schiff base derived from L-arginine and vanillin
Wasfi Aboud Al-Masoudi (1,*)



(1) Department of Physiology, Pharmacology and Chemistry, College of Veterinary Medicine, University of Basrah, Basrah, 61001, Iraq
(2) Department of Physiology, Pharmacology and Chemistry, College of Veterinary Medicine, University of Basrah, Basrah, 61001, Iraq
(3) Department of Physiology, Pharmacology and Chemistry, College of Veterinary Medicine, University of Basrah, Basrah, 61001, Iraq
(*) Corresponding Author
Received: 25 Mar 2016 | Revised: 26 Apr 2016 | Accepted: 29 Apr 2016 | Published: 30 Sep 2016 | Issue Date: September 2016
Abstract
Condensation of L-arginine with 4-hydroxy-3-methoxy benzaldehyde (vanillin) yielded a novel Schiff base derivative of arginine in good yield. This new Schiff base was characterized by elemental analysis, IR and 1H NMR spectroscopy. The toxicity of the compound was also assayed via the determination of their LD50 value by using Dixon method. Studied compound was found to have an LD50 of 718.6 mg/kg of body weight.
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European Journal of Chemistry
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DOI: 10.5155/eurjchem.7.3.280-282.1431
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Department of Physiology, Pharmacology and Chemistry, College of Veterinary Medicine, Al-Basrah University, Iraq
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European Journal of Chemistry 2016, 7(3), 280-282 | doi: https://doi.org/10.5155/eurjchem.7.3.280-282.1431 | Get rights and content
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