European Journal of Chemistry 2017, 8(2), 155-161. doi:10.5155/eurjchem.8.2.155-161.1564

Synthesis, characterization and biological activity study of some new palladium(II) complexes containing amine or azomethine groups


Adil Ali Al-Fregi (1,*) , Ahmed Laith Al-Fadhly (2) , Bushra Kamel Al-Salami (3)

(1) Department of Chemistry, College of Science, University of Basrah, 61001, Basrah, Iraq
(2) Department of Chemistry, College of Science, University of Basrah, 61001, Basrah, Iraq
(3) Department of Chemistry, College of Science, University of Basrah, 61001, Basrah, Iraq
(*) Corresponding Author

Received: 09 Mar 2017, Accepted: 19 Apr 2017, Published: 30 Jun 2017

Abstract


This study reports the preparative methods of two types of palladium(II) complexes. The first method revealed two newly palladium (II) complexes derived from bidentate amine ligands, and the second one describes six newly palladium(II) complexes derived from bidentate Schiff base ligands. All the synthesized complexes have been characterized by elemental analysis, conductivity measurements, UV-Visible, FT-IR and 1H NMR spectral data. In vitro, all the synthesized complexes have been tested for their growth inhibitory activity against Gram negative bacteria Escherichia coli and Gram positive Staphylococcus aureus as well as determining the minimum inhibitory concentration. In addition, the interactions between compounded complexes and human DNA were also studied.


Keywords


Schiff base; Amine ligands; Antibacterial activity; Bidentate amine ligands; Palladium(II) complexes; Human DNA interactions

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DOI: 10.5155/eurjchem.8.2.155-161.1564

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How to cite


Al-Fregi, A.; Al-Fadhly, A.; Al-Salami, B. Eur. J. Chem. 2017, 8(2), 155-161. doi:10.5155/eurjchem.8.2.155-161.1564
Al-Fregi, A.; Al-Fadhly, A.; Al-Salami, B. Synthesis, characterization and biological activity study of some new palladium(II) complexes containing amine or azomethine groups. Eur. J. Chem. 2017, 8(2), 155-161. doi:10.5155/eurjchem.8.2.155-161.1564
Al-Fregi, A., Al-Fadhly, A., & Al-Salami, B. (2017). Synthesis, characterization and biological activity study of some new palladium(II) complexes containing amine or azomethine groups. European Journal of Chemistry, 8(2), 155-161. doi:10.5155/eurjchem.8.2.155-161.1564
Al-Fregi, Adil, Ahmed Laith Al-Fadhly, & Bushra Kamel Al-Salami. "Synthesis, characterization and biological activity study of some new palladium(II) complexes containing amine or azomethine groups." European Journal of Chemistry [Online], 8.2 (2017): 155-161. Web. 23 Oct. 2019
Al-Fregi, Adil, Al-Fadhly, Ahmed, AND Al-Salami, Bushra. "Synthesis, characterization and biological activity study of some new palladium(II) complexes containing amine or azomethine groups" European Journal of Chemistry [Online], Volume 8 Number 2 (30 June 2017)

DOI Link: https://doi.org/10.5155/eurjchem.8.2.155-161.1564

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