

Synthesis of coumarin derivative using polymer supported reagents
Chiheb Mhiri (1)




(1) Laboratory of Applied Chemistry and Natural Substances Resources and Environment, Faculty of Sciences, University of Carthage, Zarzouna‐Bizerta, 7021, Tunisia
(2) Laboratory of Applied Chemistry and Natural Substances Resources and Environment, Faculty of Sciences, University of Carthage, Zarzouna‐Bizerta, 7021, Tunisia
(3) Chemistry Department, College of Science and Arts, Qassim University, Al-Rass, 51921, Kingdom of Saudi Arabia
(4) Laboratory of Applied Chemistry and Natural Substances Resources and Environment, Faculty of Sciences, University of Carthage, Zarzouna‐Bizerta, 7021, Tunisia
(*) Corresponding Author
Received: 01 Mar 2018 | Revised: 25 Mar 2018 | Accepted: 31 Mar 2018 | Published: 30 Jun 2018 | Issue Date: June 2018
Abstract
Recently, there has been a surge in use of polymer-supported reagents and catalysts become common tools for organic synthesis in what is known as polymer-assisted synthesis since they can simplify product isolation and purification. In this context, coumarin derivative 3 was prepared in good yield and high purity, starting from 3-methoxy salicylaldehyde, using reagents supported on a macroporous ion exchange resin. For this purpose, iminocoumarin and unsaturated nitrile were used as starting materials. The synthesized compounds were characterized by IR, NMR and mass spectrometry.
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DOI: 10.5155/eurjchem.9.2.89-91.1691
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Citations
[1]. José Cuevas, Rubén Seoane-Rivero, Rodrigo Navarro, Ángel Marcos-Fernández
Coumarins into Polyurethanes for Smart and Functional Materials
Polymers 12(3), 630, 2020
DOI: 10.3390/polym12030630

[2]. Francesca Annunziata, Cecilia Pinna, Sabrina Dallavalle, Lucia Tamborini, Andrea Pinto
An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities
International Journal of Molecular Sciences 21(13), 4618, 2020
DOI: 10.3390/ijms21134618

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DOI Link: https://doi.org/10.5155/eurjchem.9.2.89-91.1691

















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