European Journal of Chemistry

Synthesis of coumarin derivative using polymer supported reagents

Article Sidebar

PDF
Published: Jun 30, 2018
DOI: https://doi.org/10.5155/eurjchem.9.2.89-91.1691
Keywords:
Iminocoumarin, Selective synthesis, Unsaturated nitrile, Knoevenagel condensation, 3-Methoxy salicylaldehyde, Polymer supported reagent
Section
Research Article
Issue
Vol. 9 No. 2 (2018): June 2018
Dates
Received 2018-03-01
Accepted 2018-03-31
Published 2018-06-30
Crossmark


Main Article Content

Chiheb Mhiri
Laboratory of Applied Chemistry and Natural Substances Resources and Environment, Faculty of Sciences, University of Carthage, Zarzouna‐Bizerta, 7021, Tunisia
http://orcid.org/0000-0001-6331-6393
Riadh Ternane
Laboratory of Applied Chemistry and Natural Substances Resources and Environment, Faculty of Sciences, University of Carthage, Zarzouna‐Bizerta, 7021, Tunisia
http://orcid.org/0000-0003-3557-7558
Naceur Hamdi
Chemistry Department, College of Science and Arts, Qassim University, Al-Rass, 51921, Kingdom of Saudi Arabia
http://orcid.org/0000-0003-0110-9588
Lassaad Baklouti
Laboratory of Applied Chemistry and Natural Substances Resources and Environment, Faculty of Sciences, University of Carthage, Zarzouna‐Bizerta, 7021, Tunisia
http://orcid.org/0000-0002-5142-7501

Abstract

Recently, there has been a surge in use of polymer-supported reagents and catalysts become common tools for organic synthesis in what is known as polymer-assisted synthesis since they can simplify product isolation and purification. In this context, coumarin derivative 3 was prepared in good yield and high purity, starting from 3-methoxy salicylaldehyde, using reagents supported on a macroporous ion exchange resin. For this purpose, iminocoumarin and unsaturated nitrile were used as starting materials. The synthesized compounds were characterized by IR, NMR and mass spectrometry.


icon graph This Abstract was viewed 2187 times | icon graph Article PDF downloaded 852 times

How to Cite
(1)
Mhiri, C.; Ternane, R.; Hamdi, N.; Baklouti, L. Synthesis of Coumarin Derivative Using Polymer Supported Reagents. Eur. J. Chem. 2018, 9, 89-91.

Article Details

Share
Links for Article


Crossref - Scopus - Google - European PMC
Crossref
Scopus
Google Scholar
Europe PMC
References

[1]. Brahnbhatt, D. I.; Gajera, J. M.; Pandya, V. P.; Patel, M. A. Ind. J. Chem. 2007, 46(B), 869-871.

[2]. Murrey, R. D. H.; Medez, D.; Brown, S. A. The Natural coumarins occurences. Chemistry and Biochemistry, John Wiley Interscience, New York, 1982.

[3]. Bourinbaiar, A. S.; Tan, X.; Nagomy, R. Acta. Virol. 1993, 37, 241-250.

[4]. Venugopala, K. N.; Jayashree, B. S. Asian. J. Chem. 2004, 16(1), 407-411.

[5]. Luo, X.; Song, J.; Cheng, L.; Huang, D. Sci. China, Ser. B Chem. 2001, 44, 532-539.

[6]. Takadate, A.; Masuda, T.; Murata, C.; Isobe, A.; Shinohara, T.; Irikura, M.; Goya S. A. Anal. Sci. 1997, 13, 753-760.
https://doi.org/10.2116/analsci.13.753

[7]. Murata, S.; Nishimura, M.; Matsuzaki, S. Y.; Tachiya, M. Chem. Phys. Lett. 1994, 219, 200-204.
https://doi.org/10.1016/0009-2614(94)87045-4

[8]. Suppan, P. Chem. Phys. Lett. 1983, 94, 272-275.
https://doi.org/10.1016/0009-2614(83)87086-9

[9]. Nad, S.; Kumbarkar, M.; Pal, H. J. Phys. Chem. A 2003, 107, 4808-4816.
https://doi.org/10.1021/jp021543t

[10]. Kawski, A. Z. Natuforsch. A 1991, 54, 379-381.

[11]. Giri, R.; Bajaj, M. M. Curr. Sci. 1992, 62, 522-525.

[12]. Samanta, A.; Fessenden, R. W. J. Phys. Chem. A 2000, 104, 8972-8975.
https://doi.org/10.1021/jp0009960

[13]. Mhiri, C.; El Gharbi. R.; Le Bigot, Y. Synth. Commun. 1999, 29(19), 3385-3399.
https://doi.org/10.1080/00397919908085966

[14]. Cardillo, G.; Orena, M.; Porzi, G.; Sandri, S. Synthesis 1981, 793-798.
https://doi.org/10.1055/s-1981-29597

[15]. Shinkai, S.; Tsuji, H.; Hara, Y.; Manabe, O. Bull. Chem. Soc. Jpn. 1981, 54, 631-632.
https://doi.org/10.1246/bcsj.54.631

Supporting Agencies

Most read articles by the same author(s)
TrendMD

Dimensions - Altmetric - scite_ - PlumX

Downloads and views

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...
License Terms

License Terms

by-nc

Copyright © 2025 by Authors. This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at https://www.eurjchem.com/index.php/eurjchem/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution, or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (https://www.eurjchem.com/index.php/eurjchem/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).