European Journal of Chemistry

Synthesis of novel quinazolinone and fused quinazolinones

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Published: Sep 30, 2011
DOI: https://doi.org/10.5155/eurjchem.2.3.404-409.267
Keywords:
Benzoxazinone, Azine, Fused quinazolinones, Nitrogen nucleophiles, Triazinoquinazolinone, Oxadiazinoquinazolinone
Section
Research Article
Issue
Vol. 2 No. 3 (2011): September 2011
Dates
Received 2010-08-28
Accepted 2011-01-04
Published 2011-09-30


Main Article Content

Mahmoud Refaee Mahmoud
Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
Manal Mohamed El-Shahawi
Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
Fatma Saber Mohamed Abu El-Azm
Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt

Abstract

A number of novel quinazolinone derivatives have been synthesized using the readily obtainable 2-[(1Z,3E)-1-benzamido-4-phenyl-1,3-butadien-1-yl]-3,1-benzoxazin-4(H)one (1) via the reaction with different nitrogen nucleophiles such as azines, Schiff’s base, primary aromatic amines, diamines, hydrazine hydrate and hydroxylamine.

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Mahmoud, M. R.; El-Shahawi, M. M.; Abu El-Azm, F. S. M. Synthesis of Novel Quinazolinone and Fused Quinazolinones. Eur. J. Chem. 2011, 2, 404-409.

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