European Journal of Chemistry

β-Cyclodextrin mediated synthesis of 1,8-dioxooctahydroxanthenes in water

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Swapna Kokkirala
Narayana Murthy Sabbavarapu
Venkata Durga Nageswar Yadavalli


An experimentally simple, efficient Michael addition reaction was developed for the synthesis of various 1,8-dioxooctahydroxanthene derivatives with 1,3-cyclohexanedione/5,5-dimethyl 1,3-cyclohexane dione and different aldehydes by using β-cyclodextrin as a catalyst in water. A biomimetic approach was employed and the corresponding products were obtained in good to excellent yields. β-cyclodextrin can be recovered and reused upto four cycles without loss of catalytic activity.2_2_272_275_800

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How to Cite
Kokkirala, S.; Sabbavarapu, N. M.; Yadavalli, V. D. N. β-Cyclodextrin Mediated Synthesis of 1,8-Dioxooctahydroxanthenes in Water. Eur. J. Chem. 2011, 2, 272-275.

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