European Journal of Chemistry

Selective iodination of 2-acetyl-1-naphthol using iodine and iodic acid under solvent-free grinding technique

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Published: Sep 30, 2012
DOI: https://doi.org/10.5155/eurjchem.3.3.314-315.641
Keywords:
Iodine, Iodic acid, Solvent-free, Grinding technique, Selective iodination, 2-Acetyl-1-naphthol
Section
Research Article
Issue
Vol. 3 No. 3 (2012): September 2012
Dates
Received 2012-05-27
Accepted 2012-06-02
Published 2012-09-30


Main Article Content

Sainath Zangade
Department of Chemistry, Madhavrao Patil Mahavidyalaya, Palam, Prabhani, Maharashtra, 431720, India
Shyam Mokle
Laboratory of Organic Synthesis, Department of Studies in Chemistry, Yeshwant Mahavidyalaya, Nanded, Maharashtra, 431602, India
Avinash Shinde
Laboratory of Organic Synthesis, Department of Studies in Chemistry, Yeshwant Mahavidyalaya, Nanded, Maharashtra, 431602, India
Yeshwant Vibhute
Laboratory of Organic Synthesis, Department of Studies in Chemistry, Yeshwant Mahavidyalaya, Nanded, Maharashtra, 431602, India

Abstract

Selective electrophilic iodination of 2-acetyl-1-naphthol was achieved using iodine and iodic acid in combination with grinding at room temperature under solvent-free conditions to yield 1-(1-hydroxy-4-iodo-naphthalen-2-yl)-ethanone. Grinding mode of reactions has not only of interest from economical point of view, in many cases they also offer considerable advantages in terms of yield, mild reaction  conditions, selectivity and simplicity of reaction procedure.

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How to Cite
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Zangade, S.; Mokle, S.; Shinde, A.; Vibhute, Y. Selective Iodination of 2-Acetyl-1-Naphthol Using Iodine and Iodic Acid under Solvent-Free Grinding Technique. Eur. J. Chem. 2012, 3, 314-315.

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Supporting Agencies

University Grant Commission (UGC), (No. 38-267/2009), New Delhi, India
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