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Synthesis and antimicrobial activity of some novel 2-azetidinones and 4-thiazolidinones derivatives
Shivaji Chavan (1)
, Sainath Zangade (2) , Archana Vibhute (3) , Yeshwant Vibhute (4,*) (1) Laboratory of Organic Synthesis, Department of Studies in Chemistry, Yeshwant Mahavidyalaya, Nanded-431602, India
(2) Laboratory of Organic Synthesis, Department of Studies in Chemistry, Yeshwant Mahavidyalaya, Nanded-431602, India
(3) Laboratory of Organic Synthesis, Department of Studies in Chemistry, Yeshwant Mahavidyalaya, Nanded-431602, India
(4) Laboratory of Organic Synthesis, Department of Studies in Chemistry, Yeshwant Mahavidyalaya, Nanded-431602, India
(*) Corresponding Author
Received: 02 Dec 2012 | Revised: 08 Jan 2013 | Accepted: 08 Jan 2013 | Published: 30 Jun 2013 | Issue Date: June 2013
Abstract
Several 2-azetidinones 2a-e and 4-thiazolidinones 3a-e have been synthesized from halo-substituted Schiff bases using conventional as well as microwave technique. The newly synthesized compounds were established on the basis of spectroscopic technique. Further, all compounds screened for antimicrobial activity against Bacillus subtilis, Escherichia coli, Aspergillus niger and Aspergillus flavus. Most of the titled compounds show potent activity.
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European Journal of Chemistry
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DOI: 10.5155/eurjchem.4.2.98-101.714
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Funding information
University Grant Commission (No. 38‐267/2009), New Delhi, India
Citations
[1]. Essam M. Hussein, Reem I. Alsantali, Moataz Morad, Rami J. Obaid, Hatem M. Altass, Ali Sayqal, Mohamed A. S. Abourehab, Amal A. Elkhawaga, Ahmed S. M. Aboraia, Saleh A. Ahmed
Bioactive fluorenes. Part III: 2,7-dichloro-9H-fluorene-based thiazolidinone and azetidinone analogues as anticancer and antimicrobial against multidrug resistant strains agents
BMC Chemistry 14(1), , 2020
DOI: 10.1186/s13065-020-00694-2
[2]. A. N. Ayyash, Dh. Kh. Kafi, Y. K. Jabur
Synthesis of Some New Pyrrolo[3,4-f]isoindole Derivatives Bearing a 1,3-Thiazolidin-4-one Moiety
Russian Journal of Organic Chemistry 58(3), 363, 2022
DOI: 10.1134/S1070428022030149
[3]. Javeed Ahmad War, Santosh Kumar Srivastava, Savitri Devi Srivastava
Design, synthesis and molecular docking studies of some morpholine linked thiazolidinone hybrid molecules
European Journal of Chemistry 7(3), 271, 2016
DOI: 10.5155/eurjchem.7.3.271-279.1427
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DOI Link: https://doi.org/10.5155/eurjchem.4.2.98-101.714
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European Journal of Chemistry 2013, 4(2), 98-101 | doi: https://doi.org/10.5155/eurjchem.4.2.98-101.714 | Get rights and content
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