European Journal of Chemistry 2013, 4(2), 121-123 | doi: https://doi.org/10.5155/eurjchem.4.2.121-123.740 | Get rights and content

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Synthesis and spectral characterization of some heterocyclic nitrogen compounds


Mamdouh Adly Hassan (1) , Maghrabi Ali Seleem (2) , Ahmed Mohamed Mosallem Younes (3) , Mohamed Mobark Taha (4) , Abou-Bakr Haredi Abdel-Monsef (5,*)

(1) Pharmaceutical Chemistry Department, Faculty of Pharmacy, Sinai University, Arish, 45518, Egypt
(2) Chemistry Department, Faculty of Science, South Valley University, Qena, 83523, Egypt
(3) Chemistry Department, Faculty of Science, South Valley University, Qena, 83523, Egypt
(4) Chemistry Department, Faculty of Science, South Valley University, Qena, 83523, Egypt
(5) Chemistry Department, Faculty of Science, South Valley University, Qena, 83523, Egypt
(*) Corresponding Author

Received: 04 Feb 2013 | Accepted: 16 Feb 2013 | Published: 30 Jun 2013 | Issue Date: June 2013

Abstract


Quinazolines and pyrimidines are most important class of compounds and have received much attention from both synthetic and medicinal chemists, because of the diverse range of their pharmacological properties. Owing to their versatile chemotherapeutic importance, a number of quinazolin-2,4-dione derivatives were synthesized using appropriate synthetic routes and characterized by IR, 1H NMR, MS, and elemental analysis.

4_2_121_123

Keywords


Arylidine; Hydrazide; Pyrimidines; Carbon disulphide; Quinazolin-2,4-dione; Glycine ethyl ester hydrochloride

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DOI: 10.5155/eurjchem.4.2.121-123.740

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Citations

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[1]. Hamdy S. El-Sheshtawy, Aboubakr Haredi Abdelmonsef, Sayed Moustafa Abboudy, Ahmed Mohamed Mosallem Younes, Mohamed Mobark Taha, Mamdouh Adly Hassan
Synthesis, Structural, and Theoretical Studies of Quinazoline-2,4-dione Derivatives
Polycyclic Aromatic Compounds  39(3), 279, 2019
DOI: 10.1080/10406638.2017.1325747
/


[2]. Eduardo Enciso, Juan I. Sarmiento-Sánchez, Héctor S. López-Moreno, Adrián Ochoa-Terán, Ulises Osuna-Martínez, Evangelina Beltrán-López
Synthesis of new quinazolin-2,4-diones as anti-Leishmania mexicana agents
Molecular Diversity  20(4), 821, 2016
DOI: 10.1007/s11030-016-9693-8
/


[3]. Mamdouh Adly Hassan, Maghrabi Ali Seleem, Ahmed Mohamed Mosallem Younes, Mohamed Mobark Taha, Abou-Bakr Haredi Abdel-Monsef
Utility of (2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-acetic acid hydrazide in the synthesis of some heterocyclic nitrogen compounds
European Journal of Chemistry  4(2), 168, 2013
DOI: 10.5155/eurjchem.4.2.168-171.762
/


[4]. Aboubakr H. Abdelmonsef, Ahmed M. Mosallam
Synthesis, in vitro biological evaluation and in silico docking studies of new quinazolin‐2,4‐dione analogues as possible anticarcinoma agents
Journal of Heterocyclic Chemistry  57(4), 1637, 2020
DOI: 10.1002/jhet.3889
/


[5]. Aboubakr Haredi Abdelmonsef, Mahmoud Eldeeb Mohamed, Mohamed El-Naggar, Hussain Temairk, Ahmed Mohamed Mosallam
Novel Quinazolin-2,4-Dione Hybrid Molecules as Possible Inhibitors Against Malaria: Synthesis and in silico Molecular Docking Studies
Frontiers in Molecular Biosciences  7, , 2020
DOI: 10.3389/fmolb.2020.00105
/


[6]. Mohamed El-Naggar, Mahmoud Eldeeb Mohamed, Ahmed Mohamed Mosallam, Wesam Salem, Huda RM Rashdan, Aboubakr Haredi Abdelmonsef
Synthesis, Characterization, Antibacterial Activity, and Computer-Aided Design of Novel Quinazolin-2,4-dione Derivatives as Potential Inhibitors Against Vibrio cholerae
Evolutionary Bioinformatics  16, 117693431989759, 2020
DOI: 10.1177/1176934319897596
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[7]. Lumadhar Santos-Ballardo, Fernando García-Páez, Lorenzo A Picos-Corrales, Adrián Ochoa-Terán, Pedro Bastidas, Loranda Calderón-Zamora, Guadalupe Rendón-Maldonado, Ulises Osuna-Martínez, Juan I Sarmiento-Sánchez
Synthesis, biological evaluation and molecular docking of 3-substituted quinazoline-2,4(1H, 3H)-diones
Journal of Chemical Sciences  132(1), , 2020
DOI: 10.1007/s12039-020-01813-1
/


[8]. Bhawana Sharma, Preeti Singh, Ashawani Kumar Singh, Satish K. Awasthi
Advancement of Chimeric Hybrid Drugs to Cure Malaria Infection: An Overview with Special Emphasis on Endoperoxide Pharmacophores
European Journal of Medicinal Chemistry  , 113408, 2021
DOI: 10.1016/j.ejmech.2021.113408
/


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How to cite


Hassan, M.; Seleem, M.; Younes, A.; Taha, M.; Abdel-Monsef, A. Eur. J. Chem. 2013, 4(2), 121-123. doi:10.5155/eurjchem.4.2.121-123.740
Hassan, M.; Seleem, M.; Younes, A.; Taha, M.; Abdel-Monsef, A. Synthesis and spectral characterization of some heterocyclic nitrogen compounds. Eur. J. Chem. 2013, 4(2), 121-123. doi:10.5155/eurjchem.4.2.121-123.740
Hassan, M., Seleem, M., Younes, A., Taha, M., & Abdel-Monsef, A. (2013). Synthesis and spectral characterization of some heterocyclic nitrogen compounds. European Journal of Chemistry, 4(2), 121-123. doi:10.5155/eurjchem.4.2.121-123.740
Hassan, Mamdouh, Maghrabi Ali Seleem, Ahmed Mohamed Mosallem Younes, Mohamed Mobark Taha, & Abou-Bakr Haredi Abdel-Monsef. "Synthesis and spectral characterization of some heterocyclic nitrogen compounds." European Journal of Chemistry [Online], 4.2 (2013): 121-123. Web. 13 Apr. 2021
Hassan, Mamdouh, Seleem, Maghrabi, Younes, Ahmed, Taha, Mohamed, AND Abdel-Monsef, Abou-Bakr. "Synthesis and spectral characterization of some heterocyclic nitrogen compounds" European Journal of Chemistry [Online], Volume 4 Number 2 (30 June 2013)

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DOI Link: https://doi.org/10.5155/eurjchem.4.2.121-123.740

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