European Journal of Chemistry

Glycerol mediated, one pot, multicomponent synthesis of dihydropyrano[2,3-c]pyrazoles

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Harvinder Singh Sohal
Arun Goyal
Rajeev Sharma
Rajshree Khare
Sanjay Kumar


Multi component, one pot synthesis of various dihydropyrano[2,3-c]pyrazole derivatives from the condensation of ethyl acetoacetate, hydrazine, aromatic aldehyde and malononitrile has been described using glycerol, as environmentally benign, economical, and easily available solvent. The targeted molecules are obtained in excellent yield without use of any additional catalyst.


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Sohal, H. S.; Goyal, A.; Sharma, R.; Khare, R.; Kumar, S. Glycerol Mediated, One Pot, Multicomponent Synthesis of dihydropyrano[2,3-c]pyrazoles. Eur. J. Chem. 2013, 4, 450-453.

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Supporting Agencies

University Grants Commission (Sanction No. F.No.8-2 (52)/2011 (MRP/NCRB)), New Delhi, India

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