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Catalyst free, one-pot, facile synthesis of novel pyrazolo-1,4-dihydropyridine derivative form pyranopyrazoles
Harvinder Singh Sohal (1,*)
, Arun Goyal (2) , Rajshree Khare (3) , Kishanpal Singh (4) , Rajeev Sharma (5) (1) Department of Chemistry, Maharishi Markandeshwar University, Mullana, 133207, Haryana, India
(2) Department of Chemistry, Maharishi Markandeshwar University, Mullana, 133207, Haryana, India
(3) Department of Chemistry, Maharishi Markandeshwar University, Mullana, 133207, Haryana, India
(4) Department of Chemistry, Punjabi University, Patiala, 147001, Punjab, India
(5) Department of Chemistry, Multani Mal Modi College, Patiala, 147001, Punjab, India
(*) Corresponding Author
Received: 11 Nov 2013 | Revised: 26 Dec 2013 | Accepted: 28 Dec 2013 | Published: 30 Jun 2014 | Issue Date: June 2014
Abstract
One pot synthesis of pyrazolo-1,4-dihydropyridine derivatives from pyranopyrazoles using acidic solvent system is described. The targeted molecules were obtained in good to excellent yield without the use of expensive catalysts, toxic solvents and chromatographic separation. The generality and functional tolerance of this convergent and environmentally benign method is demonstrated.
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DOI: 10.5155/eurjchem.5.2.227-232.967
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Maharishi Markandeshwar University, Mullana-133 207, Haryana, India
References
[1]. Hantzsch, A. Jusfus Liebigs Ann. Chem. 1882, 215, 1-82.
http://dx.doi.org/10.1002/jlac.18822150102
[2]. Hutton, R. F.; Westheimer, F. H. Tetrahedron 1958, 3, 73-74.
http://dx.doi.org/10.1016/S0040-4020(01)82613-2
[3]. Rahway, N. J. The Merck Index, 12th edition, Merck Research Laboratories, 1996.
[4]. Bostrom, S. L.; Ljung, B.; Mardh, S.; Forsen, S.; Thulin, E. Nature 1981, 292, 777-778.
http://dx.doi.org/10.1038/292777a0
[5]. Iwanami, M.; Shibanuma, T.; Fujimoto, M.; Kawai, R.; Tamazawa, K.; Takenaka, T.; Takahashi, K.; Murakami, M. Chem. Pharm. Bull. 1979, 27, 1426-1440.
http://dx.doi.org/10.1248/cpb.27.1426
[6]. Arrowsmith, J. E.; Campbell, S. F.; Cross, P. E.; Stubbs, J. K.; Burges, R. A.; Gardiner, D. G.; Blackburn, K. J. J. Med. Chem. 1986, 29, 1696-1702.
http://dx.doi.org/10.1021/jm00159a022
[7]. Goldmann, S.; Stoltefuss, J. Angew. Chem. Int. Ed. Engl. 1991, 30, 1559-1578.
http://dx.doi.org/10.1002/anie.199115591
[8]. Sunkel, C. E.; de Casa-Juana, M. F.; Santos, L.; Gomez, M. M.; Villarroya, M.; Gonzalez-Morales, M. A.; Priego, J. G.; Ortega, M. P. J. Med. Chem. 1990, 33, 3205-3210.
http://dx.doi.org/10.1021/jm00174a017
[9]. Rovnyak, G. C.; Kimball, S. D.; Beyer, B.; Cucinotta, G.; DiMarco, J. D.; Gougoutas, J.; Hedberg, A.; Malley, M.; McCarthy, J. P.; Zhang, R.; Moreland, S. J. Med. Chem. 1995, 38, 119-129.
http://dx.doi.org/10.1021/jm00001a017
[10]. Archibald, J. L.; Bradley, G.; Opalko, A.; Ward, T. J.; White, J. C.; Ennis, C.; Shapperson, N. B. J. Med. Chem. 1990, 33, 646-652.
http://dx.doi.org/10.1021/jm00164a028
[11]. Chioua, M.; Samadi, A.; Soriano, E.; Lozach, O.; Meijer, L.; Marco-Contelles, J. Bioorg. Med. Chem. Lett. 2009, 19, 4566-4569.
http://dx.doi.org/10.1016/j.bmcl.2009.06.099
[12]. Svetlik, J.; Veizerova, L.; Mayer, T. U.; Catarinella M. Bioorg. Med. Chem. Lett. 2010, 20, 4073-4076.
http://dx.doi.org/10.1016/j.bmcl.2010.05.085
[13]. Chebanov, V. A.; Sakhno, Y. I.; Desenko, S. M.; Chernenko, V. N.; Musatov, V. I.; Shishkina, S. V.; Shishkin, O. V.; Kappe, C. O. Tetrahedron 2007, 63, 1229-1242.
http://dx.doi.org/10.1016/j.tet.2006.11.048
[14]. Wang, S. L.; Liu, Y. P.; Xu, B. H.; Wang, X. H.; Jiang, B.; Tu, S. J. Tetrahedron 2011, 67, 9417-9425.
http://dx.doi.org/10.1016/j.tet.2011.09.081
[15]. Wu, L. Q.; Dong, R. Y.; Yang, C. G.; Yan, F. L. J. Chin. Chem. Soc. 2010, 57, 19-23.
[16]. Sohal, H. S.; Goyal, A.; Sharma, R.; Khare, R.; Kumar, S. Eur. J. Chem. 2013, 4, 450‐453.
http://dx.doi.org/10.5155/eurjchem.4.4.450-453.769
[17]. Sohal, H. S.; Goyal, A.; Sharma, R.; Khare, R.; Kumar, S. Curr. Trends Biotec. Chem. Res. 2013, 3, 12-16.
[18]. Kumar, S.; Goyal, A.; Sohal, H. S.; Kumar, S. Chem. Sci. Trans. 2013, 2, 1459-1465.
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DOI Link: https://doi.org/10.5155/eurjchem.5.2.227-232.967
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European Journal of Chemistry 2014, 5(2), 227-232 | doi: https://doi.org/10.5155/eurjchem.5.2.227-232.967 | Get rights and content
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