European Journal of Chemistry 2014, 5(2), 227-232 | doi: https://doi.org/10.5155/eurjchem.5.2.227-232.967 | Get rights and content






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Catalyst free, one-pot, facile synthesis of novel pyrazolo-1,4-dihydropyridine derivative form pyranopyrazoles


Harvinder Singh Sohal (1,*) , Arun Goyal (2) , Rajshree Khare (3) , Kishanpal Singh (4) , Rajeev Sharma (5)

(1) Department of Chemistry, Maharishi Markandeshwar University, Mullana, 133207, Haryana, India
(2) Department of Chemistry, Maharishi Markandeshwar University, Mullana, 133207, Haryana, India
(3) Department of Chemistry, Maharishi Markandeshwar University, Mullana, 133207, Haryana, India
(4) Department of Chemistry, Punjabi University, Patiala, 147001, Punjab, India
(5) Department of Chemistry, Multani Mal Modi College, Patiala, 147001, Punjab, India
(*) Corresponding Author

Received: 11 Nov 2013 | Revised: 26 Dec 2013 | Accepted: 28 Dec 2013 | Published: 30 Jun 2014 | Issue Date: June 2014

Abstract


One pot synthesis of pyrazolo-1,4-dihydropyridine derivatives from pyranopyrazoles using acidic solvent system is described. The targeted molecules were obtained in good to excellent yield without the use of expensive catalysts, toxic solvents and chromatographic separation. The generality and functional tolerance of this convergent and environmentally benign method is demonstrated.


Keywords


Catalyst free; Excellent yield; Acidic medium; Pyranopyrazoles; One pot synthesis; Pyrazolo-1,4-dihydropyridine

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DOI: 10.5155/eurjchem.5.2.227-232.967

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Maharishi Markandeshwar University, Mullana-133 207, Haryana, India

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How to cite


Sohal, H.; Goyal, A.; Khare, R.; Singh, K.; Sharma, R. Eur. J. Chem. 2014, 5(2), 227-232. doi:10.5155/eurjchem.5.2.227-232.967
Sohal, H.; Goyal, A.; Khare, R.; Singh, K.; Sharma, R. Catalyst free, one-pot, facile synthesis of novel pyrazolo-1,4-dihydropyridine derivative form pyranopyrazoles. Eur. J. Chem. 2014, 5(2), 227-232. doi:10.5155/eurjchem.5.2.227-232.967
Sohal, H., Goyal, A., Khare, R., Singh, K., & Sharma, R. (2014). Catalyst free, one-pot, facile synthesis of novel pyrazolo-1,4-dihydropyridine derivative form pyranopyrazoles. European Journal of Chemistry, 5(2), 227-232. doi:10.5155/eurjchem.5.2.227-232.967
Sohal, Harvinder, Arun Goyal, Rajshree Khare, Kishanpal Singh, & Rajeev Sharma. "Catalyst free, one-pot, facile synthesis of novel pyrazolo-1,4-dihydropyridine derivative form pyranopyrazoles." European Journal of Chemistry [Online], 5.2 (2014): 227-232. Web. 22 Sep. 2020
Sohal, Harvinder, Goyal, Arun, Khare, Rajshree, Singh, Kishanpal, AND Sharma, Rajeev. "Catalyst free, one-pot, facile synthesis of novel pyrazolo-1,4-dihydropyridine derivative form pyranopyrazoles" European Journal of Chemistry [Online], Volume 5 Number 2 (30 June 2014)

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DOI Link: https://doi.org/10.5155/eurjchem.5.2.227-232.967

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