European Journal of Chemistry

Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate

Article Sidebar

PDF CIF FILE
Published: Dec 22, 2010
DOI: https://doi.org/10.5155/eurjchem.1.4.289-290.207
Keywords:
Ethyl 4-(3-chlorobenzamido)benzoate, Crystal structure, Synthesis, Characterization
Section
Research Article
Issue
Vol. 1 No. 4 (2010): December 2010
Dates
Received 2010-07-16
Accepted 2010-08-07
Published 2010-12-22


Main Article Content

Aamer Saeed
Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
Hummera Rafique
Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
Ulrich Flörke
Department Chemie, Fakultät fur Naturwissenschaften, Universitat Paderborn, Warburgerstrasse 100, Paderborn, D-33098, Germany

Abstract

The title compound was efficiently synthesized in two steps starting from esterification of 4-aminobenzoic acid followed by amidation with 3-chlorobenzoyl chloride in dry tetrahydrofuran. The structure was confirmed by spectroscopic data and elemental analysis. The molecular structure was determined from single crystal X-ray diffraction data. It crystallizes in the triclinic space group P-1 with Z = 2 and unit cell dimensions a = 5.2941(15) Å, b = 8.157(2) Å, c = 16.238(4) Å, α = 82.682(6)°, β = 84.481(6)°, γ = 80.100(6)° and V = 683.2(3) Å3.

1_4_289_290_800


icon graph This Abstract was viewed 2056 times | icon graph Article PDF downloaded 896 times icon graph Article CIF FILE downloaded 0 times

How to Cite
(1)
Saeed, A.; Rafique, H.; Flörke, U. Synthesis, Characterization and Crystal Structure of Ethyl 4-(3-Chloro benzamido)benzoate. Eur. J. Chem. 2010, 1, 289-290.

Article Details

Share
Links for Article


Crossref - Scopus - Google - European PMC
Crossref
Scopus
Google Scholar
Europe PMC
References

[1]. Omar, F. A.; Mahfouz, N. M.; Rahman, M. A. Eur. J. Med. Chem. 1996, 31, 819-825.
doi:10.1016/0223-5234(96)83976-6

[2]. Amir, M.; Oberoi, A.; Alam, S. Indian J. Chem. 1999, 38B, 237-242.

[3]. Palaska, E.; Sahin, G.; Kelicen, P.; Durlu, N. T.; Altinok, G. Farmaco 2002, 57, 101-107.
doi:10.1016/S0014-827X(01)01176-4

[4]. Kumar, A.; Bansal, D.; Bajaj, K.; Sharma, S.; Archana, K.; Srivastava, V. K. Bioorg. Med. Chem. 2003, 11, 5281-5291.
doi:10.1016/S0968-0896(03)00529-7

[5]. Jackson, S.; DeGrado, W.; Dwivedi, A.; Parthasarathy, A.; Higley, A.; Krywko, J.; Rockwell, A.; Markwalder, J.; Wells, G.; Wexler, R.; Mousa, S.; Harlow, R. J. Am. Chem. Soc. 1994, 116, 3220-3230.
doi:10.1021/ja00087a007

[6]. Capdeville, R.; Buchdunger, E.; Zimmermann, J.; Matter, J. Nat. Rev. Drug Discovery. 2002, 1, 493-502.
doi:10.1038/nrd839
PMid:12120256

[7]. Manley, P. W.; Furet, P.; Bold, G.; Bruggen, J.; Mestan, J.; Meyer, T.; Schnell, C. R.; Wood, J. J. Med. Chem. 2002, 45, 5687-5693.
doi:10.1021/jm020899q
PMid:12477352

Supporting Agencies

Most read articles by the same author(s)
TrendMD

Dimensions - Altmetric - scite_ - PlumX

Downloads and views

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...
License Terms

License Terms

by-nc

Copyright © 2025 by Authors. This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at https://www.eurjchem.com/index.php/eurjchem/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution, or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (https://www.eurjchem.com/index.php/eurjchem/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).