

Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate
Aamer Saeed (1,*)



(1) Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
(2) Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
(3) Department Chemie, Fakultät fur Naturwissenschaften, Universitat Paderborn, Warburgerstrasse 100, Paderborn, D-33098, Germany
(*) Corresponding Author
Received: 16 Jul 2010 | Accepted: 07 Aug 2010 | Published: 22 Dec 2010 | Issue Date: December 2010
Abstract
The title compound was efficiently synthesized in two steps starting from esterification of 4-aminobenzoic acid followed by amidation with 3-chlorobenzoyl chloride in dry tetrahydrofuran. The structure was confirmed by spectroscopic data and elemental analysis. The molecular structure was determined from single crystal X-ray diffraction data. It crystallizes in the triclinic space group P-1 with Z = 2 and unit cell dimensions a = 5.2941(15) Å, b = 8.157(2) Å, c = 16.238(4) Å, α = 82.682(6)°, β = 84.481(6)°, γ = 80.100(6)° and V = 683.2(3) Å3.
Keywords
Full Text:
PDF

DOI: 10.5155/eurjchem.1.4.289-290.207
Links for Article
| | | | | | |
| | | | | | |
| | |
Related Articles
Article Metrics


Citations
[1]. G. Oros, M. Szőgyi, T. Cserháti
RELATIONSHIP BETWEEN THE CALCULATED PHYSICOCHEMICAL PARAMETERS AND REVERSED-PHASE THIN-LAYER CHROMATOGRAPHIC RETENTION BEHAVIOR OF ALKOXY-PHENYLBENZAMIDE DERIVATIVES
Journal of Liquid Chromatography & Related Technologies 35(10), 1314, 2012
DOI: 10.1080/10826076.2012.676948

References
[1]. Omar, F. A.; Mahfouz, N. M.; Rahman, M. A. Eur. J. Med. Chem. 1996, 31, 819-825.
doi:10.1016/0223-5234(96)83976-6
[2]. Amir, M.; Oberoi, A.; Alam, S. Indian J. Chem. 1999, 38B, 237-242.
[3]. Palaska, E.; Sahin, G.; Kelicen, P.; Durlu, N. T.; Altinok, G. Farmaco 2002, 57, 101-107.
doi:10.1016/S0014-827X(01)01176-4
[4]. Kumar, A.; Bansal, D.; Bajaj, K.; Sharma, S.; Archana, K.; Srivastava, V. K. Bioorg. Med. Chem. 2003, 11, 5281-5291.
doi:10.1016/S0968-0896(03)00529-7
[5]. Jackson, S.; DeGrado, W.; Dwivedi, A.; Parthasarathy, A.; Higley, A.; Krywko, J.; Rockwell, A.; Markwalder, J.; Wells, G.; Wexler, R.; Mousa, S.; Harlow, R. J. Am. Chem. Soc. 1994, 116, 3220-3230.
doi:10.1021/ja00087a007
[6]. Capdeville, R.; Buchdunger, E.; Zimmermann, J.; Matter, J. Nat. Rev. Drug Discovery. 2002, 1, 493-502.
doi:10.1038/nrd839
PMid:12120256
[7]. Manley, P. W.; Furet, P.; Bold, G.; Bruggen, J.; Mestan, J.; Meyer, T.; Schnell, C. R.; Wood, J. J. Med. Chem. 2002, 45, 5687-5693.
doi:10.1021/jm020899q
PMid:12477352
Supporting information
The Supplementary Material for this article can be found online at: Supplementary files
How to cite
The other citation formats (EndNote | Reference Manager | ProCite | BibTeX | RefWorks) for this article can be found online at: How to cite item
DOI Link: https://doi.org/10.5155/eurjchem.1.4.289-290.207

















European Journal of Chemistry 2010, 1(4), 289-290 | doi: https://doi.org/10.5155/eurjchem.1.4.289-290.207 | Get rights and content
Refbacks
- There are currently no refbacks.
Copyright (c)
© Copyright 2010 - 2021 • Atlanta Publishing House LLC • All Right Reserved.
The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.
Copyright 2010-2021 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 2850 Smith Ridge Trce Peachtree Cor GA 30071-2636, USA. Registered in USA.