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Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate
Aamer Saeed (1,*)
, Hummera Rafique (2) , Ulrich Flörke (3) (1) Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
(2) Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
(3) Department Chemie, Fakultät fur Naturwissenschaften, Universitat Paderborn, Warburgerstrasse 100, Paderborn, D-33098, Germany
(*) Corresponding Author
Received: 16 Jul 2010 | Accepted: 07 Aug 2010 | Published: 22 Dec 2010 | Issue Date: December 2010
Abstract
The title compound was efficiently synthesized in two steps starting from esterification of 4-aminobenzoic acid followed by amidation with 3-chlorobenzoyl chloride in dry tetrahydrofuran. The structure was confirmed by spectroscopic data and elemental analysis. The molecular structure was determined from single crystal X-ray diffraction data. It crystallizes in the triclinic space group P-1 with Z = 2 and unit cell dimensions a = 5.2941(15) Å, b = 8.157(2) Å, c = 16.238(4) Å, α = 82.682(6)°, β = 84.481(6)°, γ = 80.100(6)° and V = 683.2(3) Å3.
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DOI: 10.5155/eurjchem.1.4.289-290.207
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Citations
[1]. G. Oros, M. Szőgyi, T. Cserháti
RELATIONSHIP BETWEEN THE CALCULATED PHYSICOCHEMICAL PARAMETERS AND REVERSED-PHASE THIN-LAYER CHROMATOGRAPHIC RETENTION BEHAVIOR OF ALKOXY-PHENYLBENZAMIDE DERIVATIVES
Journal of Liquid Chromatography & Related Technologies 35(10), 1314, 2012
DOI: 10.1080/10826076.2012.676948
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DOI Link: https://doi.org/10.5155/eurjchem.1.4.289-290.207
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European Journal of Chemistry 2010, 1(4), 289-290 | doi: https://doi.org/10.5155/eurjchem.1.4.289-290.207 | Get rights and content
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