European Journal of Chemistry

Green methodologies in organic synthesis: Microwave assisted solvent- and catalyst-free synthesis of enaminones and their conversion into 1,3,5-trisubstituted benzenes as well as 3-aroyl-6-substituted pyridines



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Morsy Ahmed El-Apasery
Saleh Mohamed Al-Mousawi
Mohamed Helmy Elnagdi

Abstract

Enaminones were obtained in good yields via condensing methyl ketones with (N,N-dimethylformamide dimethyl acetal) DMF-DMA under microwave irradiation in absence of solvent. These enaminones were readily converted into 1,3,5-trisubstituted benzenes. Reacting enaminones in presence of ammonium acetate has afforded pyridine derivatives.2_2_168_172_800

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El-Apasery, M. A.; Al-Mousawi, S. M.; Elnagdi, M. H. Green Methodologies in Organic Synthesis: Microwave Assisted Solvent- and Catalyst-Free Synthesis of Enaminones and Their Conversion into 1,3,5-Trisubstituted Benzenes As Well As 3-Aroyl-6-Substituted Pyridines. Eur. J. Chem. 2011, 2, 168-172.

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