European Journal of Chemistry

Synthesis and characterization of new fatty Schiff base ethers of 4-((pyridin-3-ylmethylimino)methyl)phenol

Article Sidebar

PDF
Published: Jun 30, 2014
DOI: https://doi.org/10.5155/eurjchem.5.2.260-262.992
Keywords:
Synthesis, Schiff base, Etherification, Schiff base ether, Pyridine derivatives, Fatty alkyl bromides
Section
Research Article
Issue
Vol. 5 No. 2 (2014): June 2014
Dates
Received 2013-12-06
Accepted 2014-01-19
Published 2014-06-30


Main Article Content

Mohini Yarra
Centre for Lipid Research, Council of Scientific and Industrial Research, Indian Institute of Chemical Technology, Hyderabad, 500007, India
Badari Narayana Prasad Rachapudi
Centre for Lipid Research, Council of Scientific and Industrial Research, Indian Institute of Chemical Technology, Hyderabad, 500007, India
Sri Lakshmi Karuna Mallampalli
Centre for Lipid Research, Council of Scientific and Industrial Research, Indian Institute of Chemical Technology, Hyderabad, 500007, India

Abstract

A series of ten new Schiff base ethers were synthesized by etherification of Schiff base-{4-(pyridine-3-methylimino) methyl phenol} with fatty alkyl bromides of different chain lengths (C4-C18) in the presence of base with 80-85% isolated yields. All the synthesized Schiff base ethers (2a-j) were characterized by FT-IR, 1H NMR, 13C NMR and Mass spectral studies. Presence of a characteristic peak for ether linkage, C-O at 1039 cm-1 in IR spectra; a triplet around 7.67 ppm in 1H NMR and a characteristic peak around 69.7 in case of  13C NMR further confirmed the structures of Schiff base ethers. The structure of all the compounds were further confirmed by their characteristic molecular ion peaks in ESI-MS.


icon graph This Abstract was viewed 1785 times | icon graph Article PDF downloaded 891 times

How to Cite
(1)
Yarra, M.; Rachapudi, B. N. P.; Mallampalli, S. L. K. Synthesis and Characterization of New Fatty Schiff Base Ethers of 4-(pyridin-3-ylmethylimino)methyl)phenol. Eur. J. Chem. 2014, 5, 260-262.

Article Details

Share
Links for Article


Crossref - Scopus - Google - European PMC
Crossref
Scopus
Google Scholar
Europe PMC
References

[1]. Dhar, D. N.; Taploo, C. L. J. Sci. Ind. Res. 1982, 41, 501-506.

[2]. Bringmann, G.; Dreyer, M.; Faber, J. H.; Dalsgaard, P. W.; Staerk, D.; Jaroszewski, J. W. J. Nat. Prod. 2004, 67, 743-748.
http://dx.doi.org/10.1021/np0340549

[3]. De Souza, A. O.; Galetti, F. C. S.; Silva, C. L.; Bicalho, B.; Parma, M. M.; Fonseca, S. F. Quim. Nova 2007, 30, 1563-1566.

[4]. Guo, Z.; Xing, R.; Liu, S.; Zhong, Z.; Ji, X.; Wang, L. Carbohydr. Res. 2007, 342, 1329-1332.
http://dx.doi.org/10.1016/j.carres.2007.04.006

[5]. Przybylski, P.; Huczynski, A.; Pyta, K.; Brzezinski, B.; Bartl, F. Curr. Org. Chem. 2009, 13, 124-148.
http://dx.doi.org/10.2174/138527209787193774

[6]. Azza, A. A.; Abu, H. J. Coord. Chem. 2006, 59, 157-176.
http://dx.doi.org/10.1080/00958970500266230

[7]. Sithambaram, M. K.; Prasad, D. J.; Poojary, B, Bhat, K. S.; Holla, B. S.; Kumari, N. S. Biorg. Med. Chem, 2006, 14, 7482-7489.
http://dx.doi.org/10.1016/j.bmc.2006.07.015

[8]. Panneersevm, P.; Nair, R. R.; Vijayalakshmi, G.; Subramanian, E. H.; Sridhar, S. K. Eur. J. Med. Chem. 2005, 40, 225-229.
http://dx.doi.org/10.1016/j.ejmech.2004.09.003

[9]. Sridhar, S. K.; Saravan, M.; Ramesh, A. Eur. J. Med. Chem. 2001, 36, 615-625.
http://dx.doi.org/10.1016/S0223-5234(01)01255-7

[10]. Pandeya, S.; Saravan, M.; Nath, G.; Declercq, E. Eur. J. Pharmacol. 1999, 9, 25-31.
http://dx.doi.org/10.1016/S0928-0987(99)00038-X

[11]. Rauf, A.; Parveen, H. Ind. J. Chem. 2005, 44B, 1273-1276.

[12]. Sharma, S.; Gangal, S, Rauf, A. Eur. J. Med. Chem. 2005, 40, 173-184.
http://dx.doi.org/10.1016/j.ejmech.2004.10.003

[13]. Ahmad, S. M.; Ahmad, F.; Osman, S. M.; J. Am. Oil. Chem. Soc. 1985, 62, 1578-1580.
http://dx.doi.org/10.1007/BF02541690

[14]. Khan, M. Y. W.; Ahmad, F.; Ahmad, I.; Osman, S. M. J. Am. Oil. Chem. 1983, 60, 949-950.
http://dx.doi.org/10.1007/BF02660205

[15]. Reddy, J. R. C.; Rao, B. V. S. K.; Karuna, M. S. L.; Murthy, U. S. N.; Prasad, R. B. N. J. Am. Oil. Chem. Soc. 2013, 90, 437-448.
http://dx.doi.org/10.1007/s11746-012-2177-9

[16]. Mohini, Y.; Prasad, R. B. N.; Karuna, M. S. L.; Kumar, C. G.; Poornima, M.; Sujitha, P. Med. Chem. Res. 2013, 22, 4360-4366.
http://dx.doi.org/10.1007/s00044-012-0450-y

Supporting Agencies

The Council for Scientific Industrial Research-Indian Institute of Chemical Technology, India
Most read articles by the same author(s)

Most read articles by the same author(s)

TrendMD

Dimensions - Altmetric - scite_ - PlumX

Downloads and views

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...
License Terms

License Terms

by-nc

Copyright © 2025 by Authors. This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at https://www.eurjchem.com/index.php/eurjchem/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution, or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (https://www.eurjchem.com/index.php/eurjchem/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).