European Journal of Chemistry

Synthesis and characterization of 1-formyl-3-phenyl-5-aryl-2-pyrazolines

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Published: Sep 30, 2011
DOI: https://doi.org/10.5155/eurjchem.2.3.311-313.414
Keywords:
Chalcones, Formic acid, Pyrazolines, Hydrazine hydrate, Fluorescence spectroscopy, Spectroscopy
Section
Research Article
Issue
Vol. 2 No. 3 (2011): September 2011
Dates
Received 2011-03-07
Accepted 2011-04-07
Published 2011-09-30


Main Article Content

Assia Sid
Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
Kaddour Lamara
Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
Mahieddine Mokhtari
Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
Nouara Ziani
Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
Paul Mosset
Université de Rennes 1, Laboratoire Sciences Chimiques de Rennes, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 6226, Avenue du Général Leclerc, Rennes Cedex, 35042, France

Abstract

Reaction of chalcone derivatives 1-4 with hydrazine hydrate in presence of formic acid yielded 2-pyrazolines 5-8. Structures of these compounds have been elucidated by spectroscopic methods; IR, UV, 1H NMR, 13C NMR. Their purities were confirmed by elemental analyses.

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How to Cite
(1)
Sid, A.; Lamara, K.; Mokhtari, M.; Ziani, N.; Mosset, P. Synthesis and Characterization of 1-Formyl-3-Phenyl-5-Aryl-2-Pyrazolines. Eur. J. Chem. 2011, 2, 311-313.

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References

[1]. Zhang, X. H.; Wu, S. K.; Gao, Z. Q.; Lee, C. S.; Lee, S. T.; Kwong, H. L. Thin Solid Films 2000, 371, 40-46.
http://dx.doi.org/10.1016/S0040-6090(00)00976-7

[2]. Ramalingam, K.; Thyvekikakath, G. X.; Berlin, K. D.; Chesnut, R. W.; Brown, R. A.; Durham, N. N.; Ealick, S. E.; VanDerHelm, D. J. Med. Chem. 1977, 20, 847-850.
http://dx.doi.org/10.1021/jm00216a024
PMid:406397

[3]. Korgaokar, S. S.; Patel, P. H.; Shah, M. J.; Parekh, H. H. Indian J. Pharm. Sci. 1996, 58, 222-225.

[4]. Rajendra, P. Y.; Lakshmana, R. A.; Prasoona, L.; Murali, K.; Ravi, K. P. Bioorg. Med. Chem. Lett. 2005, 15, 5030-5034.
http://dx.doi.org/10.1016/j.bmcl.2005.08.040

[5]. Lombardino, J. G.; Otterness, I. G. J. Med. Chem. 1981, 24, 830-834.
http://dx.doi.org/10.1021/jm00139a012
PMid:7277388

[6]. Ozdemir, Z.; Kandilci, H. B.; Gumusel, B.; Calis, U.; Bilgin, A. A. Eur. J. Med. Chem. 2007, 42, 373-379.
http://dx.doi.org/10.1016/j.ejmech.2006.09.006
PMid:17069933

[7]. Taylor, E. C.; Patel, H. H. Tetrahedron 1992, 48, 8089-8100.
http://dx.doi.org/10.1016/S0040-4020(01)80479-8

[8]. Budakoti, A.; Abid, M.; Azam, A. Eur. J. Med. Chem. 2006, 41, 63-70.
http://dx.doi.org/10.1016/j.ejmech.2005.06.013
PMid:16300860

[9]. Turan-Zitouni, G.; Ozdemir, A.; Guven, K. Arch. Pharm. (Weinheim) 2005, 338, 96-104.
http://dx.doi.org/10.1002/ardp.200400935
PMid:15765490

[10]. Fathalla, O. A.; Zaki, M. E. A.; Swelam, S. A.; Nofal, S. M.; El-Eraky, W. I. Acta Pol. Pharm. 2003, 60, 51-60.
PMid:12848368

[11]. Levai, A. Monatsh. Chem. 1995, 126, 1245-1251.
http://dx.doi.org/10.1007/BF00824303

[12]. Ali, M. A.; Shaharyar, M.; Siddiqui, A. A. Eur. J. Med. Chem. 2007, 42, 268-275.
http://dx.doi.org/10.1016/j.ejmech.2006.08.004
PMid:17007966

[13]. Amir, M.; Kumar, H.; Khan, S. A. Bioorg. Med. Chem. Lett. 2008, 18, 918-922.
http://dx.doi.org/10.1016/j.bmcl.2007.12.043

[14]. Budakoti, A.; Abid, M.; Azam, A. Eur. J. Med. Chem. 2007, 42, 544-551.
http://dx.doi.org/10.1016/j.ejmech.2006.10.011
PMid:17156895

[15]. Pinto, D. C. G. A.; Silva, A. M. S.; Cavaleiro, J. A. S.; Foces-Foces, C.; Lamas-Saiz, A. L.; Jagerovic, N.; Elguero, J. Tetrahedron 1999, 55, 10187-10200.
http://dx.doi.org/10.1016/S0040-4020(99)00546-3

[16]. Toth, G.; Levai, A.; Dinya, Z.; Snatzke, G. Tetrahedron 1991, 47, 8119-8132.
http://dx.doi.org/10.1016/S0040-4020(01)91007-5

[17]. Kabesh, A.; Nyholm, R. S.; Mustafa, A.; Hilmy, M. K.; Julia, M.; Weedon, B. C. L.; Davis, W.; Ross, W. C. J.; Clar, E. J. Chem. Soc. 1951, 1951, 3254-3255.

[18]. Toth, G.; Szollosy, A.; Levai, A.; Kotovych, G. J. Chem. Soc. Perkin Trans. 2 1986, 1, 1895-1898.

[19]. Toth, G.; Levai, A.; Duddeck, H. Mag. Reson. Chem. 1992, 30, 235-239.
http://dx.doi.org/10.1002/mrc.1260300308

[20]. Toth, G.; Levai, A.; Szollosy, A.; Duddeck, H. Tetrahedron 1993, 49, 863-880.
http://dx.doi.org/10.1016/S0040-4020(01)80329-X

[21]. Kamecki, J.; Perka, W.; Pijewska, L. Polish. J. Chem. 1985, 59, 285-292.

[22]. Pijewska, L.; Kamecki, J.; Perka-Karolczak, W. Pharmazie 1993, 48, 254-257.

[23]. Sharma, T. C.; Pawar, S. R.; Reddy, N. J. Acta Chim. Hung. 1983, 112, 159-162.

[24]. Raiford, L. C.; Peterson, W. J. J. Org. Chem. 1937, 1, 544-551.
http://dx.doi.org/10.1021/jo01235a003

[25]. Singh, P; Negi, J. S.; Joshi nee Pant, G.; Rawat, M. S. M.; Budakoti, A. Molbank 2009, 3, M614-M614.
http://dx.doi.org/10.3390/M614

[26]. Levai, A. J. Heterocyl. Chem. 1998, 35, 13-16.
http://dx.doi.org/10.1002/jhet.5570350103

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