European Journal of Chemistry 2011, 2(3), 311-313 | doi: https://doi.org/10.5155/eurjchem.2.3.311-313.414 | Get rights and content

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Synthesis and characterization of 1-formyl-3-phenyl-5-aryl-2-pyrazolines


Assia Sid (1,*) , Kaddour Lamara (2) , Mahieddine Mokhtari (3) , Nouara Ziani (4) , Paul Mosset (5)

(1) Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
(2) Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
(3) Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
(4) Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
(5) Université de Rennes 1, Laboratoire Sciences Chimiques de Rennes, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 6226, Avenue du Général Leclerc, Rennes Cedex, 35042, France
(*) Corresponding Author

Received: 07 Mar 2011 | Revised: 18 Apr 2011 | Accepted: 29 Apr 2011 | Published: 30 Sep 2011 | Issue Date: September 2011

Abstract


Reaction of chalcone derivatives 1-4 with hydrazine hydrate in presence of formic acid yielded 2-pyrazolines 5-8. Structures of these compounds have been elucidated by spectroscopic methods; IR, UV, 1H NMR, 13C NMR. Their purities were confirmed by elemental analyses.

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Editor-in-Chief
European Journal of Chemistry

Keywords


Chalcones; Formic acid; Pyrazolines; Hydrazine hydrate; Fluorescence spectroscopy; Spectroscopy

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DOI: 10.5155/eurjchem.2.3.311-313.414

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Funding information


University of Oum El Bouaghi

Citations

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[1]. Ouafa Dammene Debbih, Assia Sid, Rafika Bouchene, Sofiane Bouacida, Wissam Mazouz, Noureddine Gherraf
Two hydrazones derived from 1-aryl-3-(p-substituted phenyl)prop-2-en-1-one: synthesis, crystal structure, Hirshfeld surface analysis andin vitrobiological properties
Acta Crystallographica Section C Structural Chemistry  74(6), 703, 2018
DOI: 10.1107/S2053229618006812
/


[2]. Saba Farooq, Zainab Ngaini
One-Pot and Two-Pot Synthesis of Chalcone Based Mono and Bis-Pyrazolines
Tetrahedron Letters  61(4), 151416, 2020
DOI: 10.1016/j.tetlet.2019.151416
/


[3]. Boris A. Trofimov, Elena Yu. Schmidt
Acetylenes in the Superbase-Promoted Assembly of Carbocycles and Heterocycles
Accounts of Chemical Research  51(5), 1117, 2018
DOI: 10.1021/acs.accounts.7b00618
/


[4]. Nouara Ziani, Assia Sid, Albert Demonceau, Quentin Willem, Benjamin Dassonneville, Kaddour Lamara
Synthesis of new curcumin analogues from Claisen-Schmidt condensation
European Journal of Chemistry  4(2), 146, 2013
DOI: 10.5155/eurjchem.4.2.146-148.756
/


[5]. Monika Patel, Sushmita, Akhilesh Kumar Verma
Copper-catalyzed stereo- and chemoselective synthesis of enaminones via Michael type addition
Journal of Chemical Sciences  130(6), , 2018
DOI: 10.1007/s12039-018-1465-9
/


[6]. Indu Ravish, Neera Raghav
SAR studies of differently functionalized 4′-phenylchalcone based compounds as inhibitors of cathepsins B, H and L
RSC Advances  5(62), 50440, 2015
DOI: 10.1039/C5RA00357A
/


[7]. Assia Sid, Amel Messai, Cemal Parlak, Nadide Kazancı, Dominique Luneau, Gürkan Keşan, Lydia Rhyman, Ibrahim A. Alswaidan, Ponnadurai Ramasami
1-Formyl-3-phenyl-5-(4-isopropylphenyl)-2-pyrazoline: Synthesis, characterization, antimicrobial activity and DFT studies
Journal of Molecular Structure  1121, 46, 2016
DOI: 10.1016/j.molstruc.2016.05.043
/


[8]. Assia Sid, Nouara Ziani, Ouafa Demmen-Debbih, Mahieddine Mokhtari, Kaddour Lamara
Synthesis, characterization and antimicrobial evaluation of 1-((5,3-diaryl)-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one
European Journal of Chemistry  4(3), 268, 2013
DOI: 10.5155/eurjchem.4.3.268-271.824
/


[9]. Bharat Kumar Bugata, Satya Venkata Gopala Kaladhar Dowluru, Vasudeva Rao Avupati, Venkateswara Rao Gavalapu, Divakara Laxman Somayajulu Nori, Sreenu Barla
Synthesis, characterization and in vitro biological evaluation of some new diarylsulfonylurea-chalcone hybrids as potential 5-lipoxygenase inhibitors
European Journal of Chemistry  4(4), 396, 2013
DOI: 10.5155/eurjchem.4.4.396-401.878
/


[10]. Ahmed Mutanabbi Abdula
Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives
European Journal of Chemistry  4(3), 207, 2013
DOI: 10.5155/eurjchem.4.3.207-210.780
/


[11]. Amel Haouas, Naoufel Ben Hamadi, Asma Nsira, Moncef Msadek
A Facile One Pot Synthesis of Substituted Pyrazole Derivatives
Journal of Chemical Research  37(7), 435, 2013
DOI: 10.3184/174751913X13726128889197
/


[12]. Tao Zhang, Mengya Dong, Jianjiang Zhao, Xiaofang Zhang, Xiangdong Mei
Synthesis and antifungal activity of novel pyrazolines and isoxazolines derived from cuminaldehyde
Journal of Pesticide Science  44(3), 181, 2019
DOI: 10.1584/jpestics.D19-028
/


[13]. Nouara Ziani, Kaddour Lamara, Assia Sid, Quentin Willem, Benjamin Dassonneville, Albert Demonceau
Synthesis of pyrazoline derivatives from the 1,3-dipolar cycloadditions using α,β-unsaturated cyclohexanone derivatives
European Journal of Chemistry  4(2), 176, 2013
DOI: 10.5155/eurjchem.4.2.176-179.757
/


[14]. Divakara Laxman Somayajulu Nori, Kasapu Vishnu Veera Venkata Satyanarayan, Vasudeva Rao Avupati, Bharat Kumar Bugata, Subhash Yenupuri
Synthesis, characterization and in vitro evaluation of some new 5-benzylidene-1,3-thiazolidine-2,4-dione analogs as new class of α-glucosidase inhibitors
European Journal of Chemistry  5(1), 144, 2014
DOI: 10.5155/eurjchem.5.1.144-149.925
/


References


[1]. Zhang, X. H.; Wu, S. K.; Gao, Z. Q.; Lee, C. S.; Lee, S. T.; Kwong, H. L. Thin Solid Films 2000, 371, 40-46.
http://dx.doi.org/10.1016/S0040-6090(00)00976-7

[2]. Ramalingam, K.; Thyvekikakath, G. X.; Berlin, K. D.; Chesnut, R. W.; Brown, R. A.; Durham, N. N.; Ealick, S. E.; VanDerHelm, D. J. Med. Chem. 1977, 20, 847-850.
http://dx.doi.org/10.1021/jm00216a024
PMid:406397

[3]. Korgaokar, S. S.; Patel, P. H.; Shah, M. J.; Parekh, H. H. Indian J. Pharm. Sci. 1996, 58, 222-225.

[4]. Rajendra, P. Y.; Lakshmana, R. A.; Prasoona, L.; Murali, K.; Ravi, K. P. Bioorg. Med. Chem. Lett. 2005, 15, 5030-5034.
http://dx.doi.org/10.1016/j.bmcl.2005.08.040

[5]. Lombardino, J. G.; Otterness, I. G. J. Med. Chem. 1981, 24, 830-834.
http://dx.doi.org/10.1021/jm00139a012
PMid:7277388

[6]. Ozdemir, Z.; Kandilci, H. B.; Gumusel, B.; Calis, U.; Bilgin, A. A. Eur. J. Med. Chem. 2007, 42, 373-379.
http://dx.doi.org/10.1016/j.ejmech.2006.09.006
PMid:17069933

[7]. Taylor, E. C.; Patel, H. H. Tetrahedron 1992, 48, 8089-8100.
http://dx.doi.org/10.1016/S0040-4020(01)80479-8

[8]. Budakoti, A.; Abid, M.; Azam, A. Eur. J. Med. Chem. 2006, 41, 63-70.
http://dx.doi.org/10.1016/j.ejmech.2005.06.013
PMid:16300860

[9]. Turan-Zitouni, G.; Ozdemir, A.; Guven, K. Arch. Pharm. (Weinheim) 2005, 338, 96-104.
http://dx.doi.org/10.1002/ardp.200400935
PMid:15765490

[10]. Fathalla, O. A.; Zaki, M. E. A.; Swelam, S. A.; Nofal, S. M.; El-Eraky, W. I. Acta Pol. Pharm. 2003, 60, 51-60.
PMid:12848368

[11]. Levai, A. Monatsh. Chem. 1995, 126, 1245-1251.
http://dx.doi.org/10.1007/BF00824303

[12]. Ali, M. A.; Shaharyar, M.; Siddiqui, A. A. Eur. J. Med. Chem. 2007, 42, 268-275.
http://dx.doi.org/10.1016/j.ejmech.2006.08.004
PMid:17007966

[13]. Amir, M.; Kumar, H.; Khan, S. A. Bioorg. Med. Chem. Lett. 2008, 18, 918-922.
http://dx.doi.org/10.1016/j.bmcl.2007.12.043

[14]. Budakoti, A.; Abid, M.; Azam, A. Eur. J. Med. Chem. 2007, 42, 544-551.
http://dx.doi.org/10.1016/j.ejmech.2006.10.011
PMid:17156895

[15]. Pinto, D. C. G. A.; Silva, A. M. S.; Cavaleiro, J. A. S.; Foces-Foces, C.; Lamas-Saiz, A. L.; Jagerovic, N.; Elguero, J. Tetrahedron 1999, 55, 10187-10200.
http://dx.doi.org/10.1016/S0040-4020(99)00546-3

[16]. Toth, G.; Levai, A.; Dinya, Z.; Snatzke, G. Tetrahedron 1991, 47, 8119-8132.
http://dx.doi.org/10.1016/S0040-4020(01)91007-5

[17]. Kabesh, A.; Nyholm, R. S.; Mustafa, A.; Hilmy, M. K.; Julia, M.; Weedon, B. C. L.; Davis, W.; Ross, W. C. J.; Clar, E. J. Chem. Soc. 1951, 1951, 3254-3255.

[18]. Toth, G.; Szollosy, A.; Levai, A.; Kotovych, G. J. Chem. Soc. Perkin Trans. 2 1986, 1, 1895-1898.

[19]. Toth, G.; Levai, A.; Duddeck, H. Mag. Reson. Chem. 1992, 30, 235-239.
http://dx.doi.org/10.1002/mrc.1260300308

[20]. Toth, G.; Levai, A.; Szollosy, A.; Duddeck, H. Tetrahedron 1993, 49, 863-880.
http://dx.doi.org/10.1016/S0040-4020(01)80329-X

[21]. Kamecki, J.; Perka, W.; Pijewska, L. Polish. J. Chem. 1985, 59, 285-292.

[22]. Pijewska, L.; Kamecki, J.; Perka-Karolczak, W. Pharmazie 1993, 48, 254-257.

[23]. Sharma, T. C.; Pawar, S. R.; Reddy, N. J. Acta Chim. Hung. 1983, 112, 159-162.

[24]. Raiford, L. C.; Peterson, W. J. J. Org. Chem. 1937, 1, 544-551.
http://dx.doi.org/10.1021/jo01235a003

[25]. Singh, P; Negi, J. S.; Joshi nee Pant, G.; Rawat, M. S. M.; Budakoti, A. Molbank 2009, 3, M614-M614.
http://dx.doi.org/10.3390/M614

[26]. Levai, A. J. Heterocyl. Chem. 1998, 35, 13-16.
http://dx.doi.org/10.1002/jhet.5570350103


How to cite


Sid, A.; Lamara, K.; Mokhtari, M.; Ziani, N.; Mosset, P. Eur. J. Chem. 2011, 2(3), 311-313. doi:10.5155/eurjchem.2.3.311-313.414
Sid, A.; Lamara, K.; Mokhtari, M.; Ziani, N.; Mosset, P. Synthesis and characterization of 1-formyl-3-phenyl-5-aryl-2-pyrazolines. Eur. J. Chem. 2011, 2(3), 311-313. doi:10.5155/eurjchem.2.3.311-313.414
Sid, A., Lamara, K., Mokhtari, M., Ziani, N., & Mosset, P. (2011). Synthesis and characterization of 1-formyl-3-phenyl-5-aryl-2-pyrazolines. European Journal of Chemistry, 2(3), 311-313. doi:10.5155/eurjchem.2.3.311-313.414
Sid, Assia, Kaddour Lamara, Mahieddine Mokhtari, Nouara Ziani, & Paul Mosset. "Synthesis and characterization of 1-formyl-3-phenyl-5-aryl-2-pyrazolines." European Journal of Chemistry [Online], 2.3 (2011): 311-313. Web. 4 Jun. 2023
Sid, Assia, Lamara, Kaddour, Mokhtari, Mahieddine, Ziani, Nouara, AND Mosset, Paul. "Synthesis and characterization of 1-formyl-3-phenyl-5-aryl-2-pyrazolines" European Journal of Chemistry [Online], Volume 2 Number 3 (30 September 2011)

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European Journal of Chemistry 2011, 2(3), 311-313 | doi: https://doi.org/10.5155/eurjchem.2.3.311-313.414 | Get rights and content

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