European Journal of Chemistry

Synthesis of new curcumin analogues from Claisen-Schmidt condensation

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Published: Jun 30, 2013
DOI: https://doi.org/10.5155/eurjchem.4.2.146-148.756
Keywords:
Curcumin, Spectroscopy, Benzaldehydes, Curcumin analogues, Cyclohexanone derivatives Claisen-Schmidt condensation
Section
Research Article
Issue
Vol. 4 No. 2 (2013): June 2013
Dates
Received 2013-02-21
Accepted 2013-04-05
Published 2013-06-30


Main Article Content

Nouara Ziani
Département de Chimie, Faculté des Sciences, Université Ferhat Abbas, Sétif, 19000, Algérie
Assia Sid
Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
Albert Demonceau
Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique
Quentin Willem
Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique
Benjamin Dassonneville
Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique
Kaddour Lamara
Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria

Abstract

A series of new curcumin analogues were obtained by Claisen-Schmidt condensation of substituted benzaldehydes with cyclohexanone derivatives using the ratio of 1:2 of ketone to aldehyde in dilute ethanolic solution under base catalyzed (NaOH) conditions at room temperature in good yields. The structures of the synthesized compounds were confirmed by data of IR, 1H NMR, and 13C NMR spectra.

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Ziani, N.; Sid, A.; Demonceau, A.; Willem, Q.; Dassonneville, B.; Lamara, K. Synthesis of New Curcumin Analogues from Claisen-Schmidt Condensation. Eur. J. Chem. 2013, 4, 146-148.

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Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
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