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Synthesis of pyrazoline derivatives from the 1,3-dipolar cycloadditions using α,β-unsaturated cyclohexanone derivatives
Nouara Ziani (1,*)
, Kaddour Lamara (2) , Assia Sid (3) , Quentin Willem (4) , Benjamin Dassonneville (5) , Albert Demonceau (6) (1) Département de Chimie, Faculté des Sciences, Université Ferhat Abbas, Sétif, 19000, Algérie
(2) Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
(3) Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria
(4) Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique
(5) Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique
(6) Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique
(*) Corresponding Author
Received: 21 Feb 2013 | Revised: 04 Apr 2013 | Accepted: 05 Apr 2013 | Published: 30 Jun 2013 | Issue Date: June 2013
Abstract
A series of 2-pyrazolines (3a-d) were obtained by reaction 1,3-dipolar cycloadditions of α,β-unsaturated cyclohexanone derivatives (2a-c) with hydrazine hydrate and 4-nitrophenylhydrazine in the presence of acetic acid and ethanol as solvents. The structures of the synthesized compounds were confirmed by spectroscopic methods; IR, 1H and 13C NMR.
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European Journal of Chemistry
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DOI: 10.5155/eurjchem.4.2.176-179.757
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Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria.
Citations
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