European Journal of Chemistry 2014, 5(1), 18-23. doi:10.5155/eurjchem.5.1.18-23.876

A new potentiometric sensor based on molecularly imprinted polymer for analysis of a veterinary drug imidocarb dipropionate


Mohammed Rizk (1,*) , Safaa Shafik Toubar (2) , Hossam Ezz El-Din Sayour (3) , Dalia Mohamed (4) , Rehab Moussa Touny (5)

(1) Analytical Chemistry Department, Faculty of Pharmacy-Helwan University, Ein Helwan, 11795, Cairo, Egypt
(2) Analytical Chemistry Department, Faculty of Pharmacy-Helwan University, Ein Helwan, 11795, Cairo, Egypt
(3) Analytical Chemistry Department, Animal Health Research Institute, Dokki, 12311, Giza, Egypt
(4) Analytical Chemistry Department, Faculty of Pharmacy-Helwan University, Ein Helwan, 11795, Cairo, Egypt
(5) Quality Control Department, Chemical Industries Development Company, El-Haram, 12111, Giza, Egypt
(*) Corresponding Author

Received: 13 Jul 2013, Accepted: 11 Aug 2013, Published: 31 Mar 2014

Abstract


A new potentiometric sensor based on molecularly imprinted polymer (MIP) was fabricated for the recognition and determination of imidocarb dipropionate. The MIP was synthesized using imidocarb as the template material, methacrylic acid as a functional monomer, and ethylene glycol dimethacrylate as a cross linking agent. The sensor showed a high selectivity and a sensitive response to the template molecule in aqueous solution. The MIP-electrode exhibited a near-Nernstian response in a wide concentration range 10-5 - 10-2 M with a lower detection limit of 2×10-6 M. The potentiometric conditions were carefully studied and all measuring parameters were optimized including pH, buffer type, plasticizer type, response time and stability. The applicability of the sensor was tested through potentiometric determination of imidocarb dipropionate in pure drug as well as in pharmaceutical formulation. The proposed method was statistically compared with a reported one showing no significant difference regarding accuracy and precision, which assured a good reliable novel sensor for imidocarb estimation.


Keywords


Imidox injection; Binding experiments; Potentiometric sensor; Imidocarb dipropionate; PVC polymeric membrane; Molecular imprinted polymer

Full Text:

PDF /    /


DOI: 10.5155/eurjchem.5.1.18-23.876

Article Metrics


This Abstract was viewed 1138 times | PDF Article downloaded 402 times

Citations

/


[1]. Nesrine Abdelrehim El Gohary, Adel Madbouly, Rasha Mohamed El Nashar, Boris Mizaikoff
Synthesis and application of a molecularly imprinted polymer for the voltammetric determination of famciclovir
Biosensors and Bioelectronics  65, 108, 2015
DOI: 10.1016/j.bios.2014.10.024
/


[2]. Guat Wei Lim, Jit Kang Lim, Abdul Latif Ahmad, Derek Juinn Chieh Chan
Molecularly imprinted polymer layers using Navicula sp. frustule as core material for selective recognition of lysozyme
Chemical Engineering Research and Design  101, 2, 2015
DOI: 10.1016/j.cherd.2015.06.005
/


References

[1]. Chow, C. F.; Lam, M. H. W.; Leung, M. K. P. Anal. Chim. Acta 2002, 466, 17-30.
http://dx.doi.org/10.1016/S0003-2670(02)00520-2

[2]. Martin-Esteban, A. Anal. Bioanal. Chem. 2004, 378, 1875-1875.
http://dx.doi.org/10.1007/s00216-004-2502-8

[3]. Roche, P. J. R.; Ng, S. M.; Narayanaswamy, R.; Goddard, N.; Page, K. M. Sens. Actuators B Chem. 2009, 139, 22-29.
http://dx.doi.org/10.1016/j.snb.2008.07.029

[4]. He, C. Y.; Liu, F.; Li, K. A.; Liu, H. W. Anal. Lett. 2006, 39, 275-286.
http://dx.doi.org/10.1080/00032710500476946

[5]. Yang, H. H.; Zhang, S. Q.; Tan, F.; Zhuang, Z. X.; Wang, X. R. J. Am. Chem. Soc. 2005, 127, 1378-1379.
http://dx.doi.org/10.1021/ja0467622

[6]. Chai, C.; Liu, G.; Li, F.; Liu, X.; Yao, B.; Wang, L. Anal. Chim. Acta 2010, 675, 185-190.
http://dx.doi.org/10.1016/j.aca.2010.07.012

[7]. Kriz, D.; Mosbach, K. Anal. Chim. Acta 1995, 300, 71-75.
http://dx.doi.org/10.1016/0003-2670(94)00368-V

[8]. Chen,P.; Nien, P.; Wu, C.; Wu, T.; Lin, C.; Ho, K. Anal. Chim. Acta 2009, 643, 38-44.
http://dx.doi.org/10.1016/j.aca.2009.04.004

[9]. Chen, P.; Vittal, R.; Nien, P.; Liou, G.; Ho, K. Talanta 2010, 80, 1145-1151.
http://dx.doi.org/10.1016/j.talanta.2009.08.041

[10]. Sadeghi, S.; Motaharian, A.; Moghaddam, A. Z. Sens. Actuators B Chem. 2012, 168, 336-344.
http://dx.doi.org/10.1016/j.snb.2012.04.031

[11]. Tarley, C. R. T.; Kubota, L. T. Anal. Chim. Acta 2005, 548, 11-19.
http://dx.doi.org/10.1016/j.aca.2005.05.055

[12]. Say, R.; Gultekin, A.; Ozcan, A. A.; Denizli, A.; Ersoz, A. Anal. Chim. Acta 2009, 640, 82-86.
http://dx.doi.org/10.1016/j.aca.2009.03.022

[13]. Kobayashi, T.; Murawaki, Y.; Reddy, P. S.; Abe, M.; Fujii, N. Anal. Chim. Acta 2001, 435, 141-149.
http://dx.doi.org/10.1016/S0003-2670(00)01281-2

[14]. Hao, H. X.; Zhou, H.; Chang, J.; Zhu, J.; Wei, T. X. Chin. Chem. Lett. 2011, 22, 477-480.
http://dx.doi.org/10.1016/j.cclet.2010.11.004

[15]. Sadeghi, S.; Fathi, F.; Abbasifar, J. Sens. Actuators B Chem. 2007, 122, 58-164.

[16]. Tonelli, D.; Ballarin, B.; Guadagnini, L.; Mignani, A.; Scavetta, E. Electrochim. Acta. 2011, 56, 7149-7154.
http://dx.doi.org/10.1016/j.electacta.2011.05.076

[17]. Coldham, N. G.; Moore, A. S.; Dave, M.; Graham, P. J.; Sivapathasundardm, S.; Lake, B. G.; Sauer, M. J. Drug Metab. Disp. I995, 23, 501-505.

[18]. Edelhofer, R.; Muller, A.; Schuh, M.; Obritzhauser, W.; Kanout, A. Parasitol. Res. 2004, 92, 433-435.
http://dx.doi.org/10.1007/s00436-003-1060-x

[19]. Kuttler, K. L.; Johnson, L. W. Vet. Parasitol. 1986, 21, 107-118.
http://dx.doi.org/10.1016/0304-4017(86)90151-2

[20]. Tarbin, J. A.; Shearer, G. J. Chromatogr. B. Biomed. Sci. Appl. 1992, 577, 376-381.
http://dx.doi.org/10.1016/0378-4347(92)80263-P

[21]. Ishii, R.; Takahashi, K.; Matsumoto, R. Shokuhin Eiseigaku Zasshi 2010, 52, 34-39.
http://dx.doi.org/10.3358/shokueishi.52.34

[22]. Lehner, A. F.; Hitron, J. A.; May, J.; Hughes, C.; Eisenberg, R.; Schwint, N.; Knowles, D. P.; Timoney, P.; Tobin, T. J. Anal. Toxicol. 2011, 35, 199-204.
http://dx.doi.org/10.1093/anatox/35.4.199

[23]. Koichi, I.; Mari, N.; Tomoaki, H.; Hisao, O. J. Liq. Chromatogr. Relat. Technol. 2011, 34, 2149-2156.
http://dx.doi.org/10.1080/10826076.2011.585484

[24]. Duffy, D.J.; Das, K.; Hsu, S. L.; Penelle, J.; Rotello, V. M.; Stidham, H. D. J. Am. Chem. Soc. 2002, 124, 8290-8296.
http://dx.doi.org/10.1021/ja0201146

[25]. Katz, A.; Davis, M. E. Macromolecules 1999, 32, 4113-4121.
http://dx.doi.org/10.1021/ma981445z

[26]. Umezawa, Y.; Umezawa, K.; Sato, H. Pure Appl. Chem. 1995, 67, 507-518.
http://dx.doi.org/10.1351/pac199567030507

[27]. Miller, J. C.; Miller, J. N. Statistics for Analytical Chemistry, fifth edition, Wiley, New York, 2005, p. 256.


How to cite


Rizk, M.; Toubar, S.; Sayour, H.; Mohamed, D.; Touny, R. Eur. J. Chem. 2014, 5(1), 18-23. doi:10.5155/eurjchem.5.1.18-23.876
Rizk, M.; Toubar, S.; Sayour, H.; Mohamed, D.; Touny, R. A new potentiometric sensor based on molecularly imprinted polymer for analysis of a veterinary drug imidocarb dipropionate. Eur. J. Chem. 2014, 5(1), 18-23. doi:10.5155/eurjchem.5.1.18-23.876
Rizk, M., Toubar, S., Sayour, H., Mohamed, D., & Touny, R. (2014). A new potentiometric sensor based on molecularly imprinted polymer for analysis of a veterinary drug imidocarb dipropionate. European Journal of Chemistry, 5(1), 18-23. doi:10.5155/eurjchem.5.1.18-23.876
Rizk, Mohammed, Safaa Shafik Toubar, Hossam Ezz El-Din Sayour, Dalia Mohamed, & Rehab Moussa Touny. "A new potentiometric sensor based on molecularly imprinted polymer for analysis of a veterinary drug imidocarb dipropionate." European Journal of Chemistry [Online], 5.1 (2014): 18-23. Web. 16 Sep. 2019
Rizk, Mohammed, Toubar, Safaa, Sayour, Hossam, Mohamed, Dalia, AND Touny, Rehab. "A new potentiometric sensor based on molecularly imprinted polymer for analysis of a veterinary drug imidocarb dipropionate" European Journal of Chemistry [Online], Volume 5 Number 1 (31 March 2014)

DOI Link: https://doi.org/10.5155/eurjchem.5.1.18-23.876

Refbacks

  • There are currently no refbacks.




Copyright (c)




© Copyright 2019  Atlanta Publishing House LLC All Right Reserved.

The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.

Copyright 2019 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 4614 Lavista road, Tucker, GA, 30084, USA. Registered in USA.