European Journal of Chemistry 2010, 1(1), 6-11 | doi: | Get rights and content

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Synthesis and antimicrobial activity of some new 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties

Tarik El-Sayed Ali (1,*) , Azza Mohammed El-Kazak (2)

(1) Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
(2) Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
(*) Corresponding Author

Received: 24 Mar 2010 | Accepted: 24 Mar 2010 | Published: 31 Mar 2010 | Issue Date: March 2010


Some new sulfur-nitrogen heterocyclic systems such as 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties were synthesized via heterocyclization of the key intermediate 4-(acridin-9-yl)-1-(1,2,3,4-tetrahydroacridin-9-ylcarbonyl)thiosemicarbazide. Structures of the new comp-ounds were established by elemental analyses and spectral data. All the products were also screened in vitro for their antimicrobial activity.



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European Journal of Chemistry


Acridine; 1,2,3,4-Tetrahydroacridine; S,N-heterocycles; Antimicrobial Activity

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DOI: 10.5155/eurjchem.1.1.6-11.12

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How to cite

Ali, T.; El-Kazak, A. Eur. J. Chem. 2010, 1(1), 6-11. doi:10.5155/eurjchem.1.1.6-11.12
Ali, T.; El-Kazak, A. Synthesis and antimicrobial activity of some new 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties. Eur. J. Chem. 2010, 1(1), 6-11. doi:10.5155/eurjchem.1.1.6-11.12
Ali, T., & El-Kazak, A. (2010). Synthesis and antimicrobial activity of some new 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties. European Journal of Chemistry, 1(1), 6-11. doi:10.5155/eurjchem.1.1.6-11.12
Ali, Tarik, & Azza Mohammed El-Kazak. "Synthesis and antimicrobial activity of some new 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties." European Journal of Chemistry [Online], 1.1 (2010): 6-11. Web. 4 Jun. 2023
Ali, Tarik, AND El-Kazak, Azza. "Synthesis and antimicrobial activity of some new 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties" European Journal of Chemistry [Online], Volume 1 Number 1 (31 March 2010)

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