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Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives
Hafez Mohamed El-Shaaer (1)
, Salah Abdel-Ghaffar Abdel-Aziz (2) , Faten Ismail Hanafy (3) , Tarik El-Sayed Ali (4,*) , Ali Zaky El-Fauomy (5) (1) Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
(2) Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
(3) Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
(4) Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
(5) Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
(*) Corresponding Author
Received: 01 Jan 2011 | Revised: 06 Apr 2011 | Accepted: 09 Feb 2011 | Published: 30 Jun 2011 | Issue Date: June 2011
Abstract
Some new antifungal agents have been prepared through reaction of 4-oxo-4H-chromene-3-carbaldehydes (1a,b) with some active primary amines (2a-e) and amides/thioamides (6a-d) in different conditions. Structures of the products were established on the basis of elemental analysis, IR, 1H NMR, mass spectra and semi-empirical AM1-MO calculations.
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Editor-in-Chief
European Journal of Chemistry
Keywords
Synthesis; Chromone; Chromone Derivatives; 3-Formylchromones; Antifungal activity; AM1-MO Calculation
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DOI: 10.5155/eurjchem.2.2.158-162.381
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Citations
[1]. Hafez Mohamed El-Shaaer, Salah Sayed Ibrahim, Wafaa Ramzy Abd-Elmonem, Christine Gamal Ibrahim
An efficient cyclocondensation reactions, antimicrobial activity and molecular orbital calculations of α-benzopyrone derivatives
European Journal of Chemistry 3(2), 172, 2012
DOI: 10.5155/eurjchem.3.2.172-178.582
[2]. Hafez Mohamed El-Shaaer
An efficient synthesis of some new isolated and fused 2-oxo-2H-chromene derivatives as antimicrobial and antitumor agents
European Journal of Chemistry 4(2), 138, 2013
DOI: 10.5155/eurjchem.4.2.138-145.749
[3]. H. Surya Prakash Rao, Venkata Swamy Tangeti, Lakshmi Narayana Adigopula
Synthesis and antimicrobial evaluation of 2-hydroxynaphthalene-1,4-dione and 4H-chromene conjugates
Research on Chemical Intermediates 42(10), 7285, 2016
DOI: 10.1007/s11164-016-2536-5
[4]. Nayim Sepay, Sankar P. Dey
Synthesis and Chemical Reactivity of 4‐Oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde
Journal of Heterocyclic Chemistry 51(S1), , 2014
DOI: 10.1002/jhet.2001
[5]. Fadi M. Awadallah, Tamer A. El-Waei, Mona M. Hanna, Safinaz E. Abbas, Mariangela Ceruso, Beyza Ecem Oz, Ozen Ozensoy Guler, Claudiu T. Supuran
Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives
European Journal of Medicinal Chemistry 96, 425, 2015
DOI: 10.1016/j.ejmech.2015.04.033
[6]. Hafez Mohamed El‐Shaaer, Wafaa Ramzy Abd‐Elmonem, Salah Sayed Ibrahim, Christine Gamal Ibrahim
Study of the Reactivity of 6,8‐Dimethyl‐4‐oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde Towards Amino‐6‐oxopyridine‐3‐carboxylate Derivatives
Journal of Heterocyclic Chemistry 51(S1), , 2014
DOI: 10.1002/jhet.1919
[7]. Ahmed Bari, Mohammad Khalid Parvez, Azmat Ali Khan, Amer M. Alanazi, Saeed Ali Syed, Mohammed S. Al‐Dosari, Abdulrahman M. Alobaid
A Facile One‐Pot Synthesis and Anticancer Evaluation of Novel Substituted 1,2‐Dihydropyridine and 1,2,3,4‐Tetrahydropyrimidine Analogues
Journal of Heterocyclic Chemistry 53(2), 377, 2016
DOI: 10.1002/jhet.2400
References
[1]. Ellis, G. P. Chromenes, Chromanones, and Chromones. The Chemistry of Heterocyclic Compounds; Wiley: New York, NY, Vol. 31, 1977.
[2]. Horton, D. A.; Bourne, G. T.; Smythe, M. L. Chem. Rev. 2003, 103, 893-930.
PMid:18778828
[3]. Langer, P. Synlett 2007, 7, 1016-1025.
PMid:18247406
[4]. Ali, T. E.; Abdel-Aziz, S. A.; El-Shaaer, H. M.; Hanafy, F. I.; El-Fauomy A. Z. Phosphorus, Sulfur and Silicon and the Relat. Elem. 2008, 183, 2139-2160.
PMid:19410412
[5]. Ibrahim, A. M.; Ali, T. E. J. Brazilian Chem. Soc. 2010, 2, 1007-1016.
PMid:19173350
[6]. Ghosh, C. K.; Patra, A. J. Heterocycl. Chem. 2008, 45, 1529-1547.
PMid:20018473
[7]. Sosnovskikh, V. Y.; Moshkin, V. S.; Kodess, M. I. Tetrahedron 2008, 64, 7877-7889.
PMid:20554147
[8]. Sosnovskikh, V. Y.; Irgashev, R. A.; Moshkin, V. S.; Kodess, M. I. Russ. Chem. Bull., Intern. Edition 2008, 57, 2146-2151.
[9]. El-Shaaer, H. M.; Zahradnik, P.; Lacova, M.; Matulova, M. Collect. Czech. Commun. 1994, 59, 1673-1681.
[10]. Melikyan, G. S.; Lacova, M.; Kralova, K.; El-Shaaer, H. M.; Henselova, M.; Avetisyan, A. A. Chem. Papers 1993, 47, 388-392.
PMCid:1176066
[11]. El-Shaaer, H. M.; Perjessy, A.; Zahradnik, P.; Lacova, M.; Sustekova, Z. Monatsh. Chem. 1993,124, 539-548.
[12]. Ali, T. E. Phosphorus, Sulfur, Silicon and Relat. Elem. 2007, 182, 1717-1726.
PMid:16542666
[13]. Ali, T. E.; Abdel-Aziz, S. A.; El-Shaaer, H. M.; Hanafy, F. I.; El-Fauomy, A. Z. Turk. J. Chem. 2008, 32, 365-374.
[14]. Lácová, M.; Gašparová, R.; Koiš, P.; Boháč, A.; El-Shaaer, H. M. Tetrahedron 2010, 66, 1410-1419.
[15]. Nohara, A.; Umetani, T.; Sanno, Y. Tetrahedron 1974, 30(19), 3553-3561.
PMid:19125430
[16]. Hassan, A. Y. Phosphorus, Sulfur, Silicon and the Relat. Elem. 2009, 184, 2759-2776.
[17]. Dornow, A.; Menzel, M. P. Chem. Ber. 1964, 97, 2173-2178.
PMid:9229718
[18]. Hania, M. M. E-Journal of Chemistry 2009, 6(S1), S508-S514.
[19]. Schiemenz, G. P. Chem. Ber. 1962, 95, 483-486.
[20]. Stankovicova, H.; Lacova, M.; Gaplovsky, A.; Chovancova, J.; Pronayova, N. Tetrahedron 2001, 57, 3455-3464.
[21]. Lacova, M.; Stankovicova, H.; Odlerova, Z. Farmaco 1995, 50(12), 885-888.
[22]. Rahman, A. U.; Choudhary, M. I.; Thomsen, W. J. Bioassay Techniques for Drug Development, Harwood Academic Publishers: The Netherlands 2001.
[2]. Horton, D. A.; Bourne, G. T.; Smythe, M. L. Chem. Rev. 2003, 103, 893-930.
PMid:18778828
[3]. Langer, P. Synlett 2007, 7, 1016-1025.
PMid:18247406
[4]. Ali, T. E.; Abdel-Aziz, S. A.; El-Shaaer, H. M.; Hanafy, F. I.; El-Fauomy A. Z. Phosphorus, Sulfur and Silicon and the Relat. Elem. 2008, 183, 2139-2160.
PMid:19410412
[5]. Ibrahim, A. M.; Ali, T. E. J. Brazilian Chem. Soc. 2010, 2, 1007-1016.
PMid:19173350
[6]. Ghosh, C. K.; Patra, A. J. Heterocycl. Chem. 2008, 45, 1529-1547.
PMid:20018473
[7]. Sosnovskikh, V. Y.; Moshkin, V. S.; Kodess, M. I. Tetrahedron 2008, 64, 7877-7889.
PMid:20554147
[8]. Sosnovskikh, V. Y.; Irgashev, R. A.; Moshkin, V. S.; Kodess, M. I. Russ. Chem. Bull., Intern. Edition 2008, 57, 2146-2151.
[9]. El-Shaaer, H. M.; Zahradnik, P.; Lacova, M.; Matulova, M. Collect. Czech. Commun. 1994, 59, 1673-1681.
[10]. Melikyan, G. S.; Lacova, M.; Kralova, K.; El-Shaaer, H. M.; Henselova, M.; Avetisyan, A. A. Chem. Papers 1993, 47, 388-392.
PMCid:1176066
[11]. El-Shaaer, H. M.; Perjessy, A.; Zahradnik, P.; Lacova, M.; Sustekova, Z. Monatsh. Chem. 1993,124, 539-548.
[12]. Ali, T. E. Phosphorus, Sulfur, Silicon and Relat. Elem. 2007, 182, 1717-1726.
PMid:16542666
[13]. Ali, T. E.; Abdel-Aziz, S. A.; El-Shaaer, H. M.; Hanafy, F. I.; El-Fauomy, A. Z. Turk. J. Chem. 2008, 32, 365-374.
[14]. Lácová, M.; Gašparová, R.; Koiš, P.; Boháč, A.; El-Shaaer, H. M. Tetrahedron 2010, 66, 1410-1419.
[15]. Nohara, A.; Umetani, T.; Sanno, Y. Tetrahedron 1974, 30(19), 3553-3561.
PMid:19125430
[16]. Hassan, A. Y. Phosphorus, Sulfur, Silicon and the Relat. Elem. 2009, 184, 2759-2776.
[17]. Dornow, A.; Menzel, M. P. Chem. Ber. 1964, 97, 2173-2178.
PMid:9229718
[18]. Hania, M. M. E-Journal of Chemistry 2009, 6(S1), S508-S514.
[19]. Schiemenz, G. P. Chem. Ber. 1962, 95, 483-486.
[20]. Stankovicova, H.; Lacova, M.; Gaplovsky, A.; Chovancova, J.; Pronayova, N. Tetrahedron 2001, 57, 3455-3464.
[21]. Lacova, M.; Stankovicova, H.; Odlerova, Z. Farmaco 1995, 50(12), 885-888.
[22]. Rahman, A. U.; Choudhary, M. I.; Thomsen, W. J. Bioassay Techniques for Drug Development, Harwood Academic Publishers: The Netherlands 2001.
How to cite
El-Shaaer, H.; Abdel-Aziz, S.; Hanafy, F.; Ali, T.; El-Fauomy, A.
Eur. J. Chem.
2011,
2(2), 158-162.
doi:10.5155/eurjchem.2.2.158-162.381
El-Shaaer, H.; Abdel-Aziz, S.; Hanafy, F.; Ali, T.; El-Fauomy, A. Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives.
Eur. J. Chem.
2011,
2(2), 158-162.
doi:10.5155/eurjchem.2.2.158-162.381
El-Shaaer, H., Abdel-Aziz, S., Hanafy, F., Ali, T., & El-Fauomy, A.
(2011).
Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives.
European Journal of Chemistry, 2(2), 158-162.
doi:10.5155/eurjchem.2.2.158-162.381
El-Shaaer, Hafez, Salah Abdel-Ghaffar Abdel-Aziz, Faten Ismail Hanafy, Tarik El-Sayed Ali, & Ali Zaky El-Fauomy.
"Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives." European Journal of Chemistry [Online], 2.2 (2011): 158-162. Web. 10 Dec. 2023
El-Shaaer, Hafez, Abdel-Aziz, Salah, Hanafy, Faten, Ali, Tarik, AND El-Fauomy, Ali.
"Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives" European Journal of Chemistry [Online], Volume 2 Number 2 (30 June 2011)
The other citation formats (EndNote | Reference Manager | ProCite | BibTeX | RefWorks) for this article can be found online at: How to cite item
DOI Link: https://doi.org/10.5155/eurjchem.2.2.158-162.381
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