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1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives
Reda Mohammady Abdel-Rahman (1)
, Mohammed Saleh Tawfik Makki (2) , Tarik El-Sayed Ali (3,*) , Magdy Ahmed Ibrahim (4) (1) Department of Chemistry, Faculty of Science, King Abdel-Aziz University, Jeddah, 21589, Saudi Arabia
(2) Department of Chemistry, Faculty of Science, King Abdel-Aziz University, Jeddah, 21589, Saudi Arabia
(3) Department of Chemistry, Faculty of Education, Ain shams University, Roxy, 11711, Cairo, Egypt
(4) Department of Chemistry, Faculty of Education, Ain shams University, Roxy, 11711, Cairo, Egypt
(*) Corresponding Author
Received: 10 Apr 2010 | Revised: 12 May 2010 | Accepted: 29 Jun 2010 | Published: 29 Sep 2010 | Issue Date: September 2010
Abstract
Orientation of heterocyclization reactions of functionalized 1,2,4-triazines were studied by effect of substituents in 1,2,4-triazine moieties, type of the solvent used in the reaction and the temperature effect. Also, it was found that cyclization process depended mainly on the chemoselective and regioselectivity states of the parent substrate as well as preferring cite of ring closure.
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DOI: 10.5155/eurjchem.1.3.236-245.54
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[1]. Reda Mohammady Abdel-Rahman, Mohammed Saleh Tawfik Makki, Tarik El-Sayed Ali, Magdy Ahmed Ibrahim
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[2]. Reda M. Abdel-Rahman, Abdullah M. Asiri, Salman A. Khan
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