European Journal of Chemistry 2011, 2(3), 317-323 | doi: https://doi.org/10.5155/eurjchem.2.3.317-323.420 | Get rights and content

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Reactions with hydrazonoyl halides 65: Synthesis of some new 1,3,4-thiadiazoles and triazolino[4,3-a]pyrimidines containing pyrazole moiety


Abdou Osman Abdelhamid (1,*) , Abdelgawad Ali Fahmi (2) , Karema Noury Mahmoud Halim (3)

(1) Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt
(2) Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt
(3) Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt
(*) Corresponding Author

Received: 19 Mar 2011 | Revised: 24 Apr 2011 | Accepted: 02 May 2011 | Published: 30 Sep 2011 | Issue Date: September 2011

Abstract


2,3-Dihydro-1,3,4-thiadiazoles, and triazolino[4,3-a]pyrimidines containing pyrazole moieties were prepared from the reaction of alkyl 2-[1-(4-cyano-1,5-diphenyl-1H-pyrazol-3-yl)ethylidene]hydrazinecarbodithioate and pyrimidine-2-thione derivatives with appropriate hydrazonoyl halides. The structures of all the newly synthesized compounds were confirmed by elemental analyses, spectral data, and alternative route of synthesis whenever possible.

2_3_317_323_800


Keywords


Pyrazoles; Nitrilimines; 1,3,4-Thiadiazoles; Hydrazonoyl halides; Pyrimidine-2-thione; Triazolino[4,3-a]pyrimidines

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DOI: 10.5155/eurjchem.2.3.317-323.420

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Citations

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[1]. Assia Sid, Nouara Ziani, Ouafa Demmen-Debbih, Mahieddine Mokhtari, Kaddour Lamara
Synthesis, characterization and antimicrobial evaluation of 1-((5,3-diaryl)-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one
European Journal of Chemistry  4(3), 268, 2013
DOI: 10.5155/eurjchem.4.3.268-271.824
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[2]. Abdou Osman Abdelhamid, Abdelgawad Ali Fahmi, Abeer Bahlol Ali
Reactions with hydrazonoyl halides 66: Synthesis of some new 1,3,4-thiadiazoles, triazolino[4,3-a]pyrimidines and isoxazolo[3,4-d]pyridazines containing coumarin moiety
European Journal of Chemistry  2(4), 544, 2011
DOI: 10.5155/eurjchem.2.4.544-551.478
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[3]. Abdou Osman Abdelhamid, Nadia Abdelhamid Abdel-Riheem, Tamer Tawhid El-Idreesy, Huda Refat Mahmoud Rashdan
Synthesis of 5-arylazothiazoles, pyridines and thieno[2,3-b]pyridines derivatives containing 1,2,3-triazole moiety
European Journal of Chemistry  3(3), 322, 2012
DOI: 10.5155/eurjchem.3.3.322-331.629
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[4]. M. E. A. Khalifa, M. A. Amin, M. A. N. Mosselhi
Site selectivity in reactions of hydrazonoyl halides with heterocycles containing amino and thione groups leading to fused heterocycles of potential antimicrobial activity
Russian Journal of Bioorganic Chemistry  40(1), 106, 2014
DOI: 10.1134/S1068162014010075
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[5]. Abdou Osman Abdelhamid, Abdelgawad Ali Fahmi, Amna Ali Mohamed Alsheflo
Convenient synthesis of some new pyrazolo[5,1-c]triazines, isoxazolo[3,4-d] pyrimidine and pyridine derivatives containing benzofuran moiety
European Journal of Chemistry  3(2), 129, 2012
DOI: 10.5155/eurjchem.3.2.129-137.579
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How to cite


Abdelhamid, A.; Fahmi, A.; Halim, K. Eur. J. Chem. 2011, 2(3), 317-323. doi:10.5155/eurjchem.2.3.317-323.420
Abdelhamid, A.; Fahmi, A.; Halim, K. Reactions with hydrazonoyl halides 65: Synthesis of some new 1,3,4-thiadiazoles and triazolino[4,3-a]pyrimidines containing pyrazole moiety. Eur. J. Chem. 2011, 2(3), 317-323. doi:10.5155/eurjchem.2.3.317-323.420
Abdelhamid, A., Fahmi, A., & Halim, K. (2011). Reactions with hydrazonoyl halides 65: Synthesis of some new 1,3,4-thiadiazoles and triazolino[4,3-a]pyrimidines containing pyrazole moiety. European Journal of Chemistry, 2(3), 317-323. doi:10.5155/eurjchem.2.3.317-323.420
Abdelhamid, Abdou, Abdelgawad Ali Fahmi, & Karema Noury Mahmoud Halim. "Reactions with hydrazonoyl halides 65: Synthesis of some new 1,3,4-thiadiazoles and triazolino[4,3-a]pyrimidines containing pyrazole moiety." European Journal of Chemistry [Online], 2.3 (2011): 317-323. Web. 19 Oct. 2021
Abdelhamid, Abdou, Fahmi, Abdelgawad, AND Halim, Karema. "Reactions with hydrazonoyl halides 65: Synthesis of some new 1,3,4-thiadiazoles and triazolino[4,3-a]pyrimidines containing pyrazole moiety" European Journal of Chemistry [Online], Volume 2 Number 3 (30 September 2011)

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