European Journal of Chemistry 2012, 3(4), 455-460 | doi: | Get rights and content

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Synthesis and antimicrobial activities of pyrido[2,3-d]pyrimidine, pyridotriazolopyrimidine, triazolopyrimidine, and pyrido[2,3-d:6,5d']dipyrimidine derivatives

Anhar Abdel-Aziem (1) , Marwa Sayed El-Gendy (2) , Abdou Osman Abdelhamid (3,*)

(1) Department of Chemistry, Faculty of Science (Girls), Azhar University, Nasr City, Cairo, 11754, Egypt
(2) Department of Chemistry, Faculty of Science (Girls), Azhar University, Nasr City, Cairo, 11754, Egypt
(3) Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt
(*) Corresponding Author

Received: 25 Sep 2012 | Revised: 25 Oct 2012 | Accepted: 30 Oct 2012 | Published: 31 Dec 2012 | Issue Date: December 2012


A new series of pyridotriazolopyrimidines were synthesized via reaction of hydrazonoyl halides with pyrido[2,3-d]pyrimidines. The structures of the newly synthesized compounds were established by elemental analysis, spectral data and alternative synthetic routes whenever possible. Some of synthesized compounds were also screened in vitro for their antimicrobial activity against a variety of bacterial and fungal samples.



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European Journal of Chemistry


Nitrile imines; 6-Aminothiouracil; Pyridopyrimidines; Hydrazonoyl halides; Pyridotriazolopyrimidines; Pyrido[2,3-d:6,5d']dipyrimidine

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DOI: 10.5155/eurjchem.3.4.455-460.683

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How to cite

Abdel-Aziem, A.; El-Gendy, M.; Abdelhamid, A. Eur. J. Chem. 2012, 3(4), 455-460. doi:10.5155/eurjchem.3.4.455-460.683
Abdel-Aziem, A.; El-Gendy, M.; Abdelhamid, A. Synthesis and antimicrobial activities of pyrido[2,3-d]pyrimidine, pyridotriazolopyrimidine, triazolopyrimidine, and pyrido[2,3-d:6,5d']dipyrimidine derivatives. Eur. J. Chem. 2012, 3(4), 455-460. doi:10.5155/eurjchem.3.4.455-460.683
Abdel-Aziem, A., El-Gendy, M., & Abdelhamid, A. (2012). Synthesis and antimicrobial activities of pyrido[2,3-d]pyrimidine, pyridotriazolopyrimidine, triazolopyrimidine, and pyrido[2,3-d:6,5d']dipyrimidine derivatives. European Journal of Chemistry, 3(4), 455-460. doi:10.5155/eurjchem.3.4.455-460.683
Abdel-Aziem, Anhar, Marwa Sayed El-Gendy, & Abdou Osman Abdelhamid. "Synthesis and antimicrobial activities of pyrido[2,3-d]pyrimidine, pyridotriazolopyrimidine, triazolopyrimidine, and pyrido[2,3-d:6,5d']dipyrimidine derivatives." European Journal of Chemistry [Online], 3.4 (2012): 455-460. Web. 29 May. 2023
Abdel-Aziem, Anhar, El-Gendy, Marwa, AND Abdelhamid, Abdou. "Synthesis and antimicrobial activities of pyrido[2,3-d]pyrimidine, pyridotriazolopyrimidine, triazolopyrimidine, and pyrido[2,3-d:6,5d']dipyrimidine derivatives" European Journal of Chemistry [Online], Volume 3 Number 4 (31 December 2012)

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